| 眼眶成纤维细胞与甲状腺相关眼病研究进展 |
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| 引用本文： | 代佳灵,何为民. 眼眶成纤维细胞与甲状腺相关眼病研究进展[J]. 国际眼科杂志, 2015, 15(6): 1003-1005 |
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| 作者姓名： | 代佳灵 何为民 |
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| 作者单位： | 四川大学华西医院眼科, 中国四川省成都市,610000 |
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| 基金项目： | 四川省科技计划项目资助(No.2013SZ0029); 成都市科技惠民项目资助(No.2014-HM01-00142-SF) |
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| 摘 要： | 甲状腺相关眼病的发病机制尚不完全清楚,临床缺乏确实有效的治疗方法.眼眶成纤维细胞作为靶细胞和效应细胞参与了自身免疫、炎症反应和组织重塑等多个病理过程.我们就眼眶成纤维细胞在甲状腺相关眼病发病机制中的作用的研究进展做一综述,并讨论该领域治疗研究方向.
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| 关 键 词： | 甲状腺相关眼病 眼眶成纤维细胞 自身免疫反应 |
| 收稿时间： | 2015-03-09 |
| 修稿时间： | 2015-05-12 |
Research advances of orbital fibroblasts and thyroid associated ophthalmopathy |
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| Jia-Ling Dai and Wei-Min He. Research advances of orbital fibroblasts and thyroid associated ophthalmopathy[J]. International Eye Science, 2015, 15(6): 1003-1005 |
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| Authors: | Jia-Ling Dai and Wei-Min He |
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| Affiliation: | Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China;Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610000, Sichuan Province, China |
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| Abstract: | The pathogenesis of Thyroid associated ophthalmopathy is not fully clear. Thyroid associated ophthalmopathy is lack of sustained and effective drug treatment at present. As target cells and effect cells, orbital fibroblasts are involved in the pathological processes of remodeling, inflammation and immune response in orbit tissue. The present review focuses on the study of orbital fibroblasts in the pathogenesis of thyroid related ophthalmopathy, discusses the future orientation in this field of treatment. |
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| Keywords: | thyroid associated ophthalmopathy orbital fibroblasts autoimmune |
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