煎煮条件对於槟榔煎中醚溶性生物鹼含量的影响

槟榔用作驅絛虫藥,其歷史在我國已有一千四百年之久。其驅虫效能在晚近的臨床报告上已經証实。中國藥典1953年版收載檳榔及檳榔煎为法定藥物。至於檳榔的使用剂量及煎煮方法,在一般的文献中,則各有出入。按照中國藥典1953年版的記載;檢榔煎的剂量为200—300毫升,相当於槟榔70—105克;並且规定檳榔所含醚溶性生物鹼不得少於0.25％。在一般的文献中,有謂檳榔含醚溶性生物鹼不得低於

FACTORS INFLUENCE THE ALKALOIDAL CONTENT OF ARECA DECOCTION IN ITS PREPARATION

The influence of fineness of areca powder on the assay method and on the alkaloidal content of areca decoction, the influence of the time length of decoction on the alkaloidal content and a comparison of extracting efficiency between infusion and decoction in this respect are reported with the following findings: 1. The areca powder mentioned in the Chinese Pharmacopoeia 1953, is too coarse to be used for assay purpose, while No. 60 powder gives a satisfactory result. 2. The alkaloidal content of areca decoction prepared from No. 10 powder is not much different from that of the decoction prepared from No. 20 powder. Decoction prepared from No. 40 powder shows a little increase in alkaloidal content. The loss of alkaloids during decoction is up to 52.9% of the original content used. 3. The time length for decoction (30 minutes) described in the Chinese Pharmacopoeia 1953, is reasonable. No improvement in alkaloidal content has ever been obtained even by extending the decocting period to 2 hours, while the shortening of the decocting period to 15 minutes further reduces the alkaloidal content. 4. The extracting efficiency of areca infusion is lower than that of decoction. It is interesting to note that finer powder gives infusion a smaller alkaloidal content.