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心脑舒通软胶囊的溶出度考察
引用本文:周美环,张东方,陈淼,祝峥.心脑舒通软胶囊的溶出度考察[J].云南中医学院学报,2010,33(3):41-42,46.
作者姓名:周美环  张东方  陈淼  祝峥
作者单位:1. 沈阳东北大药房连锁店,辽宁沈阳,110023
2. 中国医科大学医学院,辽宁沈阳,110001
3. 神威药业有限公司,辽宁沈阳,110003
摘    要:目的:评价心脑舒通软胶囊制剂的溶出度。方法:采用《中国药典》(2005版)溶出度测定法第二法对心脑舒通软胶囊的溶出度进行测定,以比色法对其中的总黄酮进行测定。结果:3批次心脑舒通软胶囊的溶出度分别为87.0%,(RSD%=0.3%,n=6),89.4%(RSD%=0.8%,n=6),88.8%(RSD%=1%,n=6)。结论:采用溶出度测定法第二法可测定心脑舒通软胶囊溶出度。

关 键 词:心脑舒通软胶囊  黄酮  溶出度

Xinnao Shutong Soft Capsule Dissolution Test
ZHOU Mei-huan,ZHANG Dong-fang,CHEN Miao,ZHU Zheng.Xinnao Shutong Soft Capsule Dissolution Test[J].Journal of Yunnan College of Traditional Chinese Medicine,2010,33(3):41-42,46.
Authors:ZHOU Mei-huan  ZHANG Dong-fang  CHEN Miao  ZHU Zheng
Institution:1. Shenyang North -East Drug Store Chain, Shenyang, 110023, China; 2. College of Pharmaceutical Science, China Medical University, Shenyang, 110001, China; Supply and Marketing Company, North East Pharmaceutical Group, Shenyang, 110003, China)
Abstract:Objective: To evaluate Xinnao Shutong Soft Capsule dissolution. Methods: The dissolution of Xinnao Shutong Soft Capsule was determined by No. 2 method in China Pharmacopeia (2005). Total flavone was determined by colorimetry. Results: 3 batches of dissolutions is respectively 87.0%, (RSD% = 0. 3%, n = 6), 89. 4% (RSD% =0.8%, n=6), 88.8% (RSD% =1%, n=6). Conclusion: No. 2 method in China Pharmacopeia can be used to determine the dissolution of Xinnao Shutong Soft Capsule.
Keywords:xinnao shutong soft capsule  flavone  dissolution
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