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Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of smac/DIABLO from the mitochondria
Authors:Katalin Nagy  Kinga Székely-Szüts  Kamel Izeradjene  Leslie Douglas  Mike Tillman  Helga Barti-Juhász  Massimo Dominici  Carlotta Spano  Gian Luca Cervo  Pierfranco Conte  Janet A Houghton  Rudolf Mihalik  László Kopper  István Peták MD   PhD
Affiliation:(1) 1st Department of Pathology and Experimental Cancer Research, Semmelweis University, üllői út 26., H-1085 Budapest, Hungary;(2) Molecular Pathology Research Group, Joint Research Organization of the Hungarian Academy of Science and Semmelweis University, Budapest;(3) Szentágothai János Knowledge Center, Budapest, Hungary;(4) Department of Oncology and Hematology, University of Modena and Reggio Emilia, Modena, Italy;(5) Division of Molecular Therapeutics, Department of Hematology-Oncology, St. Jude Children’s Research Hospital, Memphis, TN, USA
Abstract:
Keywords:TRAIL  epoxomicin  MG132  bortezomib/PS-341  Smac/DIABLO  colon carcinoma
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