| SLE患者血清补体第二途径激活的探讨 |
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| 引用本文： | 葛以信,薛筑云,汤意诚,张美华,贾辅忠,孙南雄,韩亚萍.SLE患者血清补体第二途径激活的探讨[J].中华皮肤科杂志,1987,20(5):270. |
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| 作者姓名： | 葛以信 薛筑云 汤意诚 张美华 贾辅忠 孙南雄 韩亚萍 |
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| 作者单位： | 1. 南京医学院一附院皮肤科;2. 南京医学院一附院传染科 |
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| 摘 要： | 本文研究SLE发病过程中血清补体替代途径的活化.对36例SLE患者同时测定血清补体ACH50,B因子、CH50,C3和C4,其结果表明除经典途径活化外,替代途径亦被激活.其B因子不仅与SLE发病有关,而且与疾病的活动性相关.B因子的变化与C3,C4变化相一致,尤其在活动性SLE.
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| 收稿时间： | 1986-07-07 |
Study the activation of alternate complement pathway in SLE |
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| Ge Yixin.Study the activation of alternate complement pathway in SLE[J].Chinese Journal of Dermatology,1987,20(5):270. |
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| Authors: | Ge Yixin |
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| Abstract: | This paper reports the study on the activation of alternate pathway of complement system during the pathological course of systemic lupus erythematosus (SLE). Serum levels of complement ACH50, B factor CH50, C3, C4 were measured in 36 patients with SLE.The results revealed that the alternate pathway of complement system in addition to the classical pathway were activated. B factor was not only related to the pathogensis of SLE but with the activity of the disease. The change of B factor correlated with the changes of C3 and C4, especially in the active phase of SLE. |
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