11例慢性荨麻疹透射电镜观察

本文报告11例慢性荨麻疹的超微结构改变.在TEM下,真皮浅层毛细血管扩张其直径约20μ,有的毛细血管见变窄,其直径约2μ.毛细血管内皮细煦肿胀,胞突变平,胞质中见多个空泡,细胞间缝隙明显可见,血管周围见少许淋巴细胞、浆细胞、肥大细胞和嗜酸细胞,可见肥大细胞脱顺粒.真皮水肿为低电子密度不定形蛋白物质,在水肿的乳头层中见肿胀的胶原微纤维,并见表皮水肿.文中对慢性荨麻疹水肿的原因进行了讨论.

TEM observation on chronic uronic ruticaria

Ultrastructural changes of chronic urticarial wheal in 11 patients are reported. It could be seen under the TEM that the capillaries of superficial dermis were dilated and had a diameter of 20μ, but some of them became narrower and with a diameter of 2μ. The endothelial cells of capillaries became edematous and their processes became flat. Many vacuoles could be found in the cytoplasm and the intercellular space widened. Scattered infiltrates of lymphocytes, plasma cells, mast cells and eosinophils could be found around the blood vessels. Degranulated mast cells could also be seen. The edematous dermis was filled with some amorphous material of low electron density. Swellen collagenous fibres could be found in the edematous papil-lary layer. The keratinocytes in the epidermis were edematous too. The causes of edema in chronic urticaria were discussed.