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EGFR gene copy number alterations are not a useful screening tool for predicting EGFR mutation status in lung adenocarcinoma
Affiliation:1. Department of Anatomical Pathology, St Vincent’s Hospital, University of Melbourne, Fitzroy, Australia;2. Molecular Pathology Research and Development Laboratory, Department of Pathology, Peter MacCallum Cancer Centre, East Melbourne, Australia;3. Department of Medical Oncology, St Vincent’s Hospital, University of Melbourne, Fitzroy, Australia;4. University of Melbourne Department of Surgery, St Vincent’s Hospital, Fitzroy, Australia;5. Department of Respiratory and Sleep Medicine, St Vincent’s Hospital, University of Melbourne, Fitzroy, Victoria, Australia;1. Aquesta Pathology, Brisbane, Australia;2. University of Queensland, Brisbane, Queensland, Australia;3. Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, University of Otago, Wellington;4. Royal Brisbane Hospital, Brisbane, Queensland, Australia;5. Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada;6. Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden;7. Department of Surgery, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand;1. Department of Pathology, University of Medicine and Pharmacy of Tirgu-Mures, Romania;2. Department of Surgery, University of Medicine and Pharmacy of Tirgu-Mures, Romania;3. Center of Tumors, National Institute of Oncology, Budapest, Hungary;1. Division of Thoracic Oncology, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Suntou-gun, Shizuoka 411-8777, Japan;2. Drug Discovery and Development Division, Shizuoka Cancer Center Research Institute, 1007 Shimonagakubo, Nagaizumi-cho, Suntou-gun, Shizuoka 411-8777, Japan;3. Division of Pathology, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Suntou-gun, Shizuoka 411-8777, Japan;4. Division of Diagnostic Radiology, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Suntou-gun, Shizuoka 411-8777, Japan;5. Division of Thoracic Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Suntou-gun, Shizuoka 411-8777, Japan;6. Department of Respiratory Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan;7. Third Department of Internal Medicine, Wakayama Medical University, 811-1 Kimiidera, Wakayama-shi, Wakayama 641-8509, Japan;1. Department of Pathology, MD Anderson Cancer Center, Houston, TX, United States;2. Department of Pathology, Brooke Army Medical Center, 3551 Roger Brooke Dr., Fort Sam Houston, TX 78234, United States;1. ICPMR, Westmead Hospital, Westmead, Australia;2. University of Western Sydney, Richmond, NSW, Australia;1. Department of Anatomical Pathology, Royal North Shore Hospital, St Leonards, Australia;2. Cancer Diagnosis and Pathology Research Group, Kolling Institute of Medial Research, St Leonards, Australia;3. Histopath Pathology, North Ryde, Australia;4. Sydney Medical School, University of Sydney, Sydney, NSW, Australia
Abstract:
Keywords:EGFR gene copy number  EGFR mutations  lung adenocarcinoma
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