| 肺癌病人手术前后外周血T淋巴细胞亚群变化的分析 |
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| 引用本文： | 胡浩,高尚志,涂仲凡,林道明,程邦昌,姚震,肖守平.肺癌病人手术前后外周血T淋巴细胞亚群变化的分析[J].武汉大学学报(医学版),1994(4). |
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| 作者姓名： | 胡浩 高尚志 涂仲凡 林道明 程邦昌 姚震 肖守平 |
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| 作者单位： | Department of Thorac and Cardiovasc Surgery，First Affiliated Hospital，Hubei Medical University，Wuhan 430060，China |
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| 摘 要： | 应用直接玫瑰花环试验对３０例肺癌病人手术前及术后１０ｄ外周血Ｔ淋巴细胞亚群的变化进行了观察。实验结果表明，术前ＣＤ＿３￣＋，ＣＤ＿４￣＋细胞百分值及ＣＤ＿４￣＋／ＣＤ＿８￣＋比值较正常对照组明显减低（Ｐ均＜０．０１）。术后１０ｄＣＤ＿３￣＋、ＣＤ＿４￣＋了细胞百分值及ＣＤ＿４￣＋／ＣＤ＿８￣＋比值较术前有所回升，但仍低于正常对照组。说明肺癌病人细胞免疫功能低下。
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| 关 键 词： | 肺肿瘤／外科手术 肺肿瘤／免疫学 T－淋巴细胞／免疫学 |
Analysis of Peripheral Blood Lymphocyte Subsets Change in the Patients with Lung Cancer |
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| Hu Hao,Gao Shangzhi,Tu Zhongfan,et al.Analysis of Peripheral Blood Lymphocyte Subsets Change in the Patients with Lung Cancer[J].Medical Journal of Wuhan University,1994(4). |
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| Authors: | Hu Hao Gao Shangzhi Tu Zhongfan |
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| Abstract: | The determination of pre-and-postoperative peripheral blood lymphocyte subsets were performed by using monoclonal antibody in the patients with lung cancer.The results showed that the percentage of CD_3￣+, CD_4￣+cell and ratio of CD_4￣+/CD_8￣+ cell on the preoperative patients were significantly lower than that of the normal group(P<0. 01, respectively).Although the percentage of CD_3￣+,CD_4￣+cell and the ratio of CD_4￣+/CD_8￣+2 were increased in the postoperatative 10 days,it was indicated that the immunity function decreased in the patients with lung cancer. |
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| Keywords: | lung neoplasms/SU lung neoplasms/IM T lymphocyte/IM |
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