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肺癌病人手术前后外周血T淋巴细胞亚群变化的分析
引用本文:胡浩,高尚志,涂仲凡,林道明,程邦昌,姚震,肖守平.肺癌病人手术前后外周血T淋巴细胞亚群变化的分析[J].武汉大学学报(医学版),1994(4).
作者姓名:胡浩  高尚志  涂仲凡  林道明  程邦昌  姚震  肖守平
作者单位:Department of Thorac and Cardiovasc Surgery,First Affiliated Hospital,Hubei Medical University,Wuhan 430060,China
摘    要:应用直接玫瑰花环试验对30例肺癌病人手术前及术后10d外周血T淋巴细胞亚群的变化进行了观察。实验结果表明,术前CD_3 ̄+,CD_4 ̄+细胞百分值及CD_4 ̄+/CD_8 ̄+比值较正常对照组明显减低(P均<0.01)。术后10dCD_3 ̄+、CD_4 ̄+了细胞百分值及CD_4 ̄+/CD_8 ̄+比值较术前有所回升,但仍低于正常对照组。说明肺癌病人细胞免疫功能低下。

关 键 词:肺肿瘤/外科手术  肺肿瘤/免疫学  T-淋巴细胞/免疫学

Analysis of Peripheral Blood Lymphocyte Subsets Change in the Patients with Lung Cancer
Hu Hao,Gao Shangzhi,Tu Zhongfan,et al.Analysis of Peripheral Blood Lymphocyte Subsets Change in the Patients with Lung Cancer[J].Medical Journal of Wuhan University,1994(4).
Authors:Hu Hao  Gao Shangzhi  Tu Zhongfan  
Abstract:The determination of pre-and-postoperative peripheral blood lymphocyte subsets were performed by using monoclonal antibody in the patients with lung cancer.The results showed that the percentage of CD_3 ̄+, CD_4 ̄+cell and ratio of CD_4 ̄+/CD_8 ̄+ cell on the preoperative patients were significantly lower than that of the normal group(P<0. 01, respectively).Although the percentage of CD_3 ̄+,CD_4 ̄+cell and the ratio of CD_4 ̄+/CD_8 ̄+2 were increased in the postoperatative 10 days,it was indicated that the immunity function decreased in the patients with lung cancer.
Keywords:lung neoplasms/SU  lung neoplasms/IM  T lymphocyte/IM
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