| 24例胃肠间质瘤病理及免疫组化分析 |
| |
| 引用本文： | 雷德利,王新海,赵晓玲,刘冬玲.24例胃肠间质瘤病理及免疫组化分析[J].肿瘤防治研究,2004,31(9):563-564,F003. |
| |
| 作者姓名： | 雷德利 王新海 赵晓玲 刘冬玲 |
| |
| 作者单位： | 1. 430033,武汉市普爱医院病理科
2. 汉川市人民医院病理科 |
| |
| 摘 要： | 目的 探讨胃肠间质瘤病理诊断及免疫组化特点。方法 对 2 4例胃肠间质瘤进行常规病理及免疫组化CD117、CD34、SMA、S 10 0染色特点分析。结果 2 4例胃肠间质瘤由梭形细胞和上皮样细胞组成 ,其中 2 1例CD117和 18例CD34标记阳性 ,阳性表达率分别为 87.5 %和 75 %。结论 胃肠间质瘤是胃肠常见的间叶性肿瘤 ,缺乏定向分化。CD117和CD34标记阳性对胃肠间质瘤的诊断具有非常重要的价值
|
| 关 键 词： | Gastrointestinal stromal tumors Immunohistis chemistry CD117 CD34 |
| 文章编号： | 1000-8578(2004)09-0563-02 |
| 收稿时间： | 2003-12-24 |
| 修稿时间： | 2004-5-11 |
Pathologic and Immunohistochemical Aanalysis of 24 Cases of Gastrointestinal Stromal Tumor |
| |
| LEI De-li,WANG Xin-Hai,ZHAO Xiao-ling,LIU Dong-ling.Pathologic and Immunohistochemical Aanalysis of 24 Cases of Gastrointestinal Stromal Tumor[J].Cancer Research on Prevention and Treatment,2004,31(9):563-564,F003. |
| |
| Authors: | LEI De-li WANG Xin-Hai ZHAO Xiao-ling LIU Dong-ling |
| |
| Institution: | LEI De-li~1,WANG Xin-Hai~2,ZHAO Xiao-ling~1,LIU Dong-ling~11.Department of Pathology,Puai Hospital of Wuhan,Wuhan 430033,China,2.People's Hospital of Hanchuan City |
| |
| Abstract: | Objective To investigate the pathologic and immunohistochemical features of CD117 CD34 SMA S-100 and diagnostic criteria of gastrointestinal stromal tumors(GIST). Methods 24 cases of GIST were studied by routine and immunohistochemistry. Results The GISTS showed two bases cell types spindle and epithelioid; 21 cases, tumor cells of GIST were positivery stained for CD117. 18 cases, tumor cells of GIST were positively stained for CD34. Conclusion GIST which have no evidence of specific differentiation constitute the largest category of mesenchymal tumous of gastointestinal tract.The expression of CD117 and CD34 play an improtant role in the diagnosis of GIST. |
| |
| Keywords: | Gastrointestinal stromal tumors Immunohistis chemistry CD117 CD34 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《肿瘤防治研究》浏览原始摘要信息 |
| 点击此处可从《肿瘤防治研究》下载免费的PDF全文 |
