| 2009年上海市甲型H1N1流感疫苗大规模人群接种免疫学效果评价 |
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| 引用本文： | 顾宝柯,于淼,陈健,蔡华,袁政安,王丹,陈昕,赵根明,刘杰,张涛.2009年上海市甲型H1N1流感疫苗大规模人群接种免疫学效果评价[J].中国预防医学杂志,2011(6):498-500. |
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| 作者姓名： | 顾宝柯 于淼 陈健 蔡华 袁政安 王丹 陈昕 赵根明 刘杰 张涛 |
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| 作者单位： | 上海市疾病预防控制中心;复旦大学公共卫生学院公共卫生安全教育部重点实验室;上海市卫生局; |
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| 摘 要： | 目的评价2009-2010年上海市甲型H1N1流行性感冒疫苗(甲流疫苗)的免疫学效果。方法以公安人员、中小学生、医务人员这三类重点人群作为免疫学评价的对象,采用分层抽样的方法在上海市4个区县抽取公安人员110人,中小学生146人,医务人员306人,于甲流疫苗接种前和接种后5~6周分别采集外周静脉血,检测甲型H1N1流感(甲流)抗体水平,进行甲流疫苗免疫学效果评价。结果总体上,甲流抗体阳性率由接种前34.9%提高到98.9%,抗体几何平均滴度(GMT)由接种前1∶17提高到1∶351,抗体≥4倍增长率为85.6%。结论 2009年上海市大规模人群接种的甲流疫苗具有良好的免疫学效果。
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| 关 键 词： | 甲型H1N1流行性感冒 甲流疫苗 免疫学效果 |
Evaluation of influenza A(H1N1) vaccination effectiveness in Shanghai,2009 |
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| GU Bao-ke,YU Miao,CHEN Jian,CAI Hua,YUAN Zheng-an,WANG Dan,CHEN Xin,ZHAO Gen-ming,LIU Jie,ZHANG Tao.Evaluation of influenza A(H1N1) vaccination effectiveness in Shanghai,2009[J].China Preventive Medicine,2011(6):498-500. |
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| Authors: | GU Bao-ke YU Miao CHEN Jian CAI Hua YUAN Zheng-an WANG Dan CHEN Xin ZHAO Gen-ming LIU Jie ZHANG Tao |
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| Institution: | GU Bao-ke,YU Miao,CHEN Jian,CAI Hua,YUAN Zheng-an,WANG Dan,CHEN Xin,ZHAO Gen-ming,LIU Jie,ZHANG Tao.Shanghai Municipal Center for Disease Control and Prevention,Shanghai 200336,China |
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| Abstract: | Objective To evaluate the effectiveness of influenza A(H1N1) virus split vaccine on a mass-vaccination program.Methods A stratified sampling method was applied to select 110 public security staff,146 elementary and high school students and 306 health care professionals.All participants were tested for influenza A antibody levels before and in 5-6 weeks after the vaccination of influenza A(H1N1).Results The positive rate of influenza A(H1N1) influenza antibody increased from 34.9% to 98.9% and the average ti... |
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| Keywords: | Influenza A(H1N1) Antibody response Vaccination effectiveness |
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