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PET/MRI of the breast
Affiliation:1. Department of Radiology and Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands;2. Department of Surgery, Maastricht University Medical Center+, Maastricht, The Netherlands;3. GROW – School for Oncology and Developmental Biology, Maastricht University Medical Center+, Maastricht, The Netherlands;4. Department of Surgery, Catharina Hospital, Eindhoven, The Netherlands;5. Department of Epidemiology, Maastricht University Medical Center+, Maastricht, The Netherlands;6. Department of Pathology, Zuyderland Hospital, Heerlen, The Netherlands;7. Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands;1. Servicio de Medicina Nuclear, Instituto de Investigación Sanitaria, Hospital Clínico San Carlos, Madrid, España;2. Servicio de Medicina Nuclear, Hospital Universitario HM Puerta del Sur, Móstoles, Madrid, España;3. Servicio de Radiología, Hospital Universitario HM Puerta del Sur, Móstoles, Madrid, España;1. Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan;2. Department of Breast Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan;1. University of Tuebingen, Department of Radiology, Diagnostic and Interventional Radiology, Germany;2. University of Tuebingen, Department of Radiology, Diagnostic and Interventional Neuroradiology, Germany;3. University of Tuebingen, Department of Radiology, Nuclear Medicine, Germany;2. Service de Radiologie, Hôpitaux Universitaires de Genève, rue Gabrielle-Perret-Gentil, Genève, Switzerland;3. Service de Radio-Oncologie, Hôpitaux Universitaires de Genève, rue Gabrielle-Perret-Gentil, Genève, Switzerland;4. Servei de Radio-Oncologia, Instituto Oncológico Teknon, Barcelona, Spain
Abstract:The future clinical use of the combination of positron emission tomography (PET) with 2-Fluoro[F-18]-2-Deoxy-d-Glucose (FDG)and MRI is still unclear. If a patient requires a PET and breast DCE-MRI for staging purposes, both scans can be done in the same visit. In the breast, DCE-MRI is better at lesion detection (sensitivity), margin evaluation, and has a higher specificity than CT. The potential for multiparametric qualitative and quantitative imaging is also an advantage of PET/MRI which provides opportunity to improve tumor characterization and may ultimately lead to outcome prediction. This review discusses technical and clinical aspects of this emerging technology in breast cancer patients.
Keywords:PET/MRI  Breast cancer  PET/CT  Multiparametric MRI
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