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Long-Term Humoral Immune Response in Persons with Asymptomatic or Mild SARS-CoV-2 Infection,Vietnam |
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| Authors: | Huynh Kim Mai Nguyen Bao Trieu Trinh Hoang Long Hoang Tien Thanh Nguyen Dinh Luong Le Xuan Huy Lam Anh Nguyet Dinh Nguyen Huy Man Danielle E. Anderson Tran Tan Thanh Nguyen Van Vinh Chau Guy Thwaites Lin-Fa Wang Le Van Tan Do Thai Hung |
| Abstract: | Antibody response against nucleocapsid and spike proteins of SARS-CoV-2 in 11 persons with mild or asymptomatic infection rapidly increased after infection. At weeks 18–30 after diagnosis, all remained seropositive but spike protein–targeting antibody titers declined. These data may be useful for vaccine development. |
| Keywords: | asymptomatic coronavirus disease COVID-19 immune response neutralizing antibodies respiratory infections SARS-CoV-2 SARS-CoV-2 spike protein viruses |