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Rapid Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 in Detention Facility,Louisiana, USA,May–June, 2020
Authors:Megan Wallace  Allison E. James  Rachel Silver  Mitsuki Koh  Farrell A. Tobolowsky  Sean Simonson  Jeremy A. W. Gold  Rena Fukunaga  Henry Njuguna  Keith Bordelon  Jonathan Wortham  Melissa Coughlin  Jennifer L. Harcourt  Azaibi Tamin  Brett Whitaker  Natalie J. Thornburg  Ying Tao  Krista Queen  Anna Uehara  Clinton R. Paden  Jing Zhang  Suxiang Tong  Danielle Haydel  Ha Tran  Kaylee Kim  Kiva A. Fisher  Mariel Marlow  Jacqueline E. Tate  Reena H. Doshi  Theresa Sokol  Kathryn G. Curran
Affiliation:Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M. Wallace, A.E. James, R. Silver, M. Koh, F.A. Tobolowsky, J.A.W. Gold, R. Fukunaga, H. Njuguna, K. Bordelon, J. Wortham, M. Coughlin, J.L. Harcourt, A. Tamin, B. Whitaker, N.J. Thornburg, Y. Tao, K. Queen, A. Uehara, C.R. Paden, J. Zhang, S. Tong, K. Kim, K.A. Fisher, M. Marlow, J.E. Tate, R.H. Doshi, K.G. Curran);Louisiana Department of Health, New Orleans, Louisiana, USA (S. Simonson, D. Haydel, H. Tran, T. Sokol)
Abstract:To assess transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a detention facility experiencing a coronavirus disease outbreak and evaluate testing strategies, we conducted a prospective cohort investigation in a facility in Louisiana, USA. We conducted SARS-CoV-2 testing for detained persons in 6 quarantined dormitories at various time points. Of 143 persons, 53 were positive at the initial test, and an additional 58 persons were positive at later time points (cumulative incidence 78%). In 1 dormitory, all 45 detained persons initially were negative; 18 days later, 40 (89%) were positive. Among persons who were SARS-CoV-2 positive, 47% (52/111) were asymptomatic at the time of specimen collection; 14 had replication-competent virus isolated. Serial SARS-CoV-2 testing might help interrupt transmission through medical isolation and quarantine. Testing in correctional and detention facilities will be most effective when initiated early in an outbreak, inclusive of all exposed persons, and paired with infection prevention and control.
Keywords:severe acute respiratory syndrome coronavirus 2   SARS-CoV-2   coronaviruses   viruses   coronavirus disease   COVID-19   correctional facilities   detention facilities   serial testing   transmission   respiratory infections   zoonoses   Louisiana   United States
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