Predictors of outcome after catheter ablation for atrial fibrillation: Group analysis categorized by age and type of atrial fibrillation |
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| Authors: | Tetsuya Uemura MD Hidekazu Kondo MD PhD Hiroki Sato MD PhD Masaki Takahashi MD Tetsuji Shinohara MD PhD Kazuki Mitarai MD Akira Fukui MD PhD Kei Hirota MD Tomoko Fukuda MD Nozomi Kodama MD Miho Miyoshi MD Naoko Ogawa MD Masato Wada MD Hirochika Yamasaki MD Kenzo Iwanaga MD Akihiro Uno MD Katsunori Tawara MD Keisuke Yonezu MD Hidefumi Akioka MD PhD Yasushi Teshima MD PhD Kunio Yufu MD PhD Mikiko Nakagawa MD PhD Naohiko Takahashi MD PhD |
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| Affiliation: | Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, Japan |
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| Abstract: | Background The outcome of catheter ablation could probably differ among patients with atrial fibrillation (AF), depending on age and AF type. We aimed to investigate the difference in predictors of outcome after catheter ablation for AF among the patient categories divided by age and AF type. Methods and Results A total of 396 patients with AF (mean age 65.69 ± 11.05 years, 111 women [28.0%]) who underwent catheter ablation from January 2018 to December 2019 were retrospectively analyzed. We divided the patients into four categories: patients with paroxysmal AF (PAF) or persistent AF (PeAF) who were 75 years or younger (≤75 years) or older than 75 years (>75 years). Kaplan–Meier survival analysis demonstrated that patients with PAF aged ≤75 years had the lowest AF recurrence among the four groups (log-rank test, p = .0103). In the patients with PAF aged ≤75 years (N = 186, 46.7%), significant factors associated with recurrence were female sex (p = .008) and diabetes (p = .042). In the patients with PeAF aged ≤75 years (N = 142, 35.9%), the only significant factor associated with no recurrence was medication with a renin-angiotensin system inhibitor (p = .044). In the patients with PAF aged >75 years (N = 53, 14.4%), diabetes was significantly associated with AF recurrence (p = .021). No significant parameters were found in the patients with PeAF aged >75 years (N = 15, 4.1%). Conclusions Our findings indicate that the risk factors for AF recurrence after catheter ablation differed by age and AF type. |
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| Keywords: | age catheter ablation paroxysmal atrial fibrillation persistent atrial fibrillation recurrence |
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