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吡噻旺钠的制备及处方设计
引用本文:常志初, 蒋勤, 徐炳祥, 马振赢. 吡噻旺钠的制备及处方设计[J]. 中国现代应用药学, 1997, (2): 46-47.
作者姓名:常志初  蒋勤  徐炳祥  马振赢
作者单位:解放军第一○二医院!常州,213003(常志初,蒋勤),第二军医大学药学院!上海,213003(徐炳祥),上海工业微生物研究所!上海,213003(马振赢)
摘    要:合成了吡噻旺钠,并将其配成1%的稀醇液,考察了其在该溶液中的稳定性,测得该处方中吡噻旺钠的t0.9为1.81a。

关 键 词:吡噻旺钠  制备  稳定性

The Prescription Design and Clinical Trall of MPO-Na
Chang zhi-chun et al. The Prescription Design and Clinical Trall of MPO-Na[J]. The Chinese Journal of Modern Applied Pharmacy, 1997, 0(2): 46-47
Authors:Chang zhi-chun et al
Abstract:To cbtain more potent and wide-spectrum agent, 2-mercaptopyridinai 1-oxidesodium (MPO-Na,I) was, synthesized, the minimum inhibitory concentrations of this compoundagainst 12 mycotic stiams were 0.25-10 pprn. The t0.9 of MPO-Na (1%) in the solution ofalcohol (40%) was 1.81 year. 56 patients were involved in the trail of MPO-Na (1%) solution,the total effective rate was 94. 64%.
Keywords:MPO-Na  stability  MIC  effective rate
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