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Respiratory pulse pressure variation fails to predict fluid responsiveness in acute respiratory distress syndrome |
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| Authors: | Karim Lakhal Stephan Ehrmann Dalila Benzekri-Lefèvre Isabelle Runge Annick Legras Pierre-François Dequin Emmanuelle Mercier Michel Wolff Bernard Régnier Thierry Boulain |
| Institution: | 1. Service de réanimation médicale et maladies infectieuses, H?pital Bichat-Claude Bernard, Assistance Publique des H?pitaux de Paris, 18 rue Henri Huchard, F-75018, Paris, France 2. Service de réanimation médicale polyvalente, centre hospitalier régional universitaire de Tours, 2 boulevard Tonnelé, F-37044, Tours, France 3. Service de réanimation médicale, H?pital La Source, centre hospitalier régional, avenue de l’H?pital, F-45067, Orléans, cedex 1, France |
| Abstract: | IntroductionFluid responsiveness prediction is of utmost interest during acute respiratory distress syndrome (ARDS), but the performance of respiratory pulse pressure variation (ΔRESPPP) has scarcely been reported. In patients with ARDS, the pathophysiology of ΔRESPPP may differ from that of healthy lungs because of low tidal volume (Vt), high respiratory rate, decreased lung and sometimes chest wall compliance, which increase alveolar and/or pleural pressure. We aimed to assess ΔRESPPP in a large ARDS population. |
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