Activated protein C in septic shock: a propensity-matched analysis |
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Authors: | Farid Sadaka Jacklyn O’Brien Matthew Migneron Julie Stortz Alexander Vanston Robert W Taylor |
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Affiliation: | (1) St. John’s Mercy Medical Center, St Louis University, 621 S New Ballas Rd., Suite 4006B, 63141 St. Louis, MO, USA |
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Abstract: | Introduction The use of human recombinant activated protein C (rhAPC) for the treatment of severe sepsis remains controversial despite multiple reported trials. The efficacy of rhAPC remains a matter of dispute. We hypothesized that patients with septic shock who were treated with rhAPC had an improved in-hospital mortality compared to patients with septic shock with similar acuity who did not receive rhAPC. |
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