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探索应用节段生物电阻抗法评价血液透析患者容量状况
引用本文:刘婧,周亦伦,孙芳,马丽洁,沈洋,韩彬,刘文虎,崔太根.探索应用节段生物电阻抗法评价血液透析患者容量状况[J].中国血液净化,2010,9(2):84-87.
作者姓名:刘婧  周亦伦  孙芳  马丽洁  沈洋  韩彬  刘文虎  崔太根
作者单位:1. 首都医科大学附属北京朝阳医院肾内科,北京,100020
2. 首都医科大学附属北京友谊医院肾内科,北京,100050
摘    要:目的探索应用改良的节段生物电阻抗法-小腿电阻抗比值(CBIR)评估血液透析(HD)患者的容量状况。方法使用多频生物电阻抗分析仪测定157例健康志愿者右侧小腿的电阻抗值,计算CBIR(impedance 200k/impedance 5k)作为容量负荷指标,并确定正常参考值范围。同时检测117例HD患者透析后CBIR,观察患者容量负荷状况。结果健康志愿者的CBIR为(0.774±0.028),由此确定正常参考值范围为0.746~0.802(均数±1个标准差)。HD组透析后CBIR明显高于正常对照组(0.790±0.033)vs(0.774±0.028),P0.001],其中容量增高者(CBIR0.802)、容量正常者(CBIR在0.746~0.802)和容量降低者(CBIR0.746)分别占36.8%,53.0%,10.2%。在使用降压药的剂量无显著差异的情况下,CBIR增高组高血压的发生率明显高于CBIR正常组(P=0.008)和CBIR降低组(P=0.003)。结论小腿电阻抗检测可能是评估HD患者容量状况的有效方法。

关 键 词:生物电阻抗  血液透析  容量状况

Application of modified segmental bioimpedance spectroscopy for estimation of volume status in hemodialysis patients
LIU Jing,ZHOU Yi-un,SUN Fang,MA Li-jie,SHEN Yang,HAN Bin,LIU Wen-hu,CUI Tai-gen.Application of modified segmental bioimpedance spectroscopy for estimation of volume status in hemodialysis patients[J].Chinese Journal of Blood Purification,2010,9(2):84-87.
Authors:LIU Jing  ZHOU Yi-un  SUN Fang  MA Li-jie  SHEN Yang  HAN Bin  LIU Wen-hu  CUI Tai-gen
Institution:LIU Jing1,ZHOU Yi-1un1,SUN Fang1,MA Li-jie1,SHEN Yang1,HAN Bin1,LIU Wen-hu2,CUI Tai-gen1.1Department of Nephrology,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020 China,2Department of Nephrology,Beijing Friendship Hospital,Beijing 100050,China
Abstract:Objective To evaluate volume status in hemodialysis(HD) patients by modified bioimpedance spectroscopy-calf bioimpedance ratio(CBIR).Methods Calf bioimpedance was measured by bioimpedance spectroscopy.As an index of volume status,CBIR was calculated as follows:CBIR = impedance of 200 kHz/impedance of 5kHz.Reference CBIR range was obtained from 157 healthy volunteers.The volume status of 117 HD patients post-dialysis was assessed using the CBIR from healthy volunteers as the reference CBIR range.Results CBIR...
Keywords:Hemodialysis  Bioimpedance  Volume status  
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