CA125在卵巢恶性肿瘤诊治中的临床意义

目的：探讨CA125在卵巢恶性肿瘤诊治中的临床价值。方法：采用磁分离酶免疫法测定41例卵巢恶性肿瘤及174例其他妇科疾病患者血清CA125水平，并将这些妇科疾病患者的CA125水平与卵巢恶性肿瘤进行对比。结果：卵巢恶性肿瘤及结核性腹膜炎患者血清CA125均明显升高，两者相比，差异无显著性（P＞0．05）；子宫颈癌及子宫内膜异位症患者血清CA125轻度升高，但与卵巢恶性肿瘤相比，差异有极显著性（P＜0．01）；子宫肌瘤、子宫内膜癌、卵巢良性肿瘤及单纯卵巢囊肿、盆腔炎性包块患者血清CA125一般在正常范围（＜25U／ml)。结论：CA125在卵巢恶性肿瘤诊断中具有较高的特异性和准确性，可用于卵巢癌的筛查、诊断、监测及判断预后，尤以筛查及监测最重要。

MEASUREMENT OF CA125 IN SERUM OF PATIENTS WITH OVARY MALIGNANT TUMORS

Objective: To probe into the significance of CA 125 in diagnosis of ovary malignant tumors. Method: The concentration of CA 125 in sera of 41 patients with ovary malignant tumors and 174 ones with other female illnesses (control group) was measured with IEMA. Result: The concentration of CA 125 increased significantly in the patients with ovary malignant tumors and peritoneal tuberculosis, and there was not any significant difference between them. But there were very significant differences of CA 125 level between the malignant tumors and other illnesses except the peritoneal tuberculosis. Conclusion: CA 125 is a special and sensitive serum marker for the diagnosis and following-up of ovary malignant tumors, but it must be noticed the differential diagnosis from peritoneal tuberculosis.