52例老年吸入性肺炎治疗效果评价 |
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引用本文: | 刘广杰,赵玉霞,胥杰,陈晓. 52例老年吸入性肺炎治疗效果评价[J]. 中国综合临床, 2005, 25(1): 716-718. DOI: 10.3760/cma.j.issn.1008-6315.2009.07.018 |
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作者姓名: | 刘广杰 赵玉霞 胥杰 陈晓 |
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作者单位: | 首都医科大学附属北京同仁医院呼吸内科,100730;中国医科大学附属第一医院; |
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摘 要: | Objective To evaluate the efficacy of administration of ampicillin/sulbactam and imipenem/cilastatin in treatment of aspiration pneumonia in aged patients. Methods 26 aged patients was treated with aspira-tion pneumonia (2.25~3.00 g) through vessel injection twice perday,and another 26 patients was treated with imi-penem/cilastatin (0.5 g) through vessile injection every 6~8 hours. We evaluated the efficacy through assessing the temperature,the chest radiography,WBC and CRP,incidence of side effects,the time to cure and the clearance of bacteria. Results The cure rate was 84.6% (22/26) and 92.3% (24/26),respectively (χ2=0.19,P=0.66). The time to cure was 8.2±2.8 days and 7.5±1.6 days for the groups (t=1.107,P=0.274). Gastrointestinal side effects were observed in the group of ampicillin/sulbactarn;slight abnormality of liver function occurred in the group of imipenem/cilastatin ;all above adverse effects in two groups were rapidly and completely disappeared after therapy stopped. Conclusion Both ampicillin/sulbactam and imipenem/cilastatin are effective antibiotics to treat aspiration pneumonia in aged patients.
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关 键 词: | 吸入性肺炎 氨苄西林/舒巴坦钠 亚胺培南/西司他丁钠 |
Evaluation of clinical treatment of aspiration pneumonia in aged patients |
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Keywords: | Aspiration pneumoniaAmpicillin/sulbactamImipenem/cilastatin |
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