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Idiopathic pulmonary hemosiderosis in adults

Authors:	Maalej S Drira I Fennira H Ben Mefteh R Bourguiba M Zidi A El Mezni F Ben Kheder A

Affiliation:	1. Service de Pneumologie, Hôpital de Pneumo-Phtisiologie Abderrahman-Mami, 2080 L’Ariana/Tunis, Tunisie;2. Service de Radiologie, Hôpital de Pneumo-Phtisiologie Abderrahman-Mami, 2080 L’Ariana/Tunis, Tunisie;3. Service d’Anatomie Pathologique, Hôpital de Pneumo-Phtisiologie Abderrahman-Mami, 2080 L’Ariana/Tunis, Tunisie;1. Respiratory Service, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet sn, 08916, Badalona, Barcelona;2. Department of Radiology, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet sn, 08916, Badalona, Barcelona;3. Fundació Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Barcelona;4. CibeRes–Ciber de Enfermedades Respiratorias, Bunyola, Bunyola, Mallorca;5. Department of Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain;1. Department of Microbiology and Immunology, Graduate School of Medicine, Hokkaido University, Kita-ku, Sapporo 060-8638, Japan;2. Laboratory for Gut Homeostasis, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan;1. Department of Medicine and Surgery, Section of Respiratory Diseases, University of Salerno, Salerno, Italy;2. Department of Cardiothoracic and Respiratory Sciences, Second University of Naples, Naples, Italy;3. Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy;4. Department of Mental and Physical Health and Preventive Medicine, Second University of Naples, Naples, Italy;1. Grady Memorial Hospital, Emory University School of Medicine, 49 Jesse Hill Junior Drive, Atlanta, GA 30303, USA;2. Division of Pulmonary and Critical Care Medicine, Medical College of Wisconsin, Milwaukee, WI 53188, USA;3. Critical Care Fellowship Program, Medical Intensive Care Unit, Division of Pulmonary and Critical Care Medicine, Suite E 5200, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA;1. Department of Respiratory Medicine, Fukuoka University Hospital, 7-45-1 Nanakuma, Fukuoka-city, Fukuoka 814-0180, Japan;2. Department of Respiratory Medicine and Infectious Diseases, Oita University Hospital, Hasama-machi, Oita 879-5593, Japan

Abstract:	Idiopathic pulmonary hemosiderosis (IPH) is a rare cause of diffuse alveolar hemorrhage characterized by abnormal deposition of hemosiderin iron in the macrophages of alveoli. Most cases occur in children. In adults, IPH is rare: almost 10 cases reported during the late 10 years. We report the case of a 20-year-old-girl with IPH. There was no evidence of pulmonary vasculitis or capillaritis. Long-term treatment with systemic corticosteroids was followed by clinical remission lasting 4 years.

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