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泽泻降脂有效部位提取工艺的筛选研究
引用本文:周本杰,莫轩辉.泽泻降脂有效部位提取工艺的筛选研究[J].中国药房,2006,17(2):103-105.
作者姓名:周本杰  莫轩辉
作者单位:1. 南方医科大学珠江医院药剂科,广州市,510282
2. 广州星群药业股份有限公司,广州市,510280
摘    要:目的:筛选泽泻降脂有效部位的最佳提取工艺。方法:采用正交试验设计,以泽泻所含三萜类总苷元的紫外吸收为指标,考察乙醇浓度、提取时间、提取次数、乙醇用量4种因素对提取结果的影响。结果:泽泻降脂有效部位的最佳提取工艺为5倍药材量的90%乙醇提取2次,每次提取2h。结论:该提取工艺合理、可行。

关 键 词:泽泻  降脂有效部位  正交试验  提取工艺
文章编号:1001-0408(2006)02-0103-03
收稿时间:08 15 2005 12:00AM
修稿时间:09 13 2005 12:00AM

Study on Extraction Technique for Blood Lipid Lowering Effective Components in Rhizoma Alismatis
ZHOU Benjie,MO Xuanhui.Study on Extraction Technique for Blood Lipid Lowering Effective Components in Rhizoma Alismatis[J].China Pharmacy,2006,17(2):103-105.
Authors:ZHOU Benjie  MO Xuanhui
Institution:1.Dept. of Pharmacy ,Zhujiang Hospital, Southern University of Medical Sciences, Guangzhou510282, China;2.Guangzhou Xingqun Pharmaceutical Co.LTD., Guangzhou 510280, China
Abstract:OBJECTIVE: To screen the optimal extraction technique for the blood-lipid lowering effective components in rhizoma alismatis.METHODS: In an orthogonal test, the influence of 4 factors: alcohol concentration, extraction time, extraction frequency, and alcohol dosage, on the extraction was investigated by using the value of ultraviolet absorption of total triterpenes sapogenins in rhizoma alismatis as the investigated index.RESULTS: The optimal extraction technique for blood-lipid lowering effective components in rhizoma alismatis was to extract the medicinal material in 90% alcohol 5 times the amount of the material for 2 times with 2 hours for each time.CONCLUSION: The extraction technique is reasonable and practicable.
Keywords:Rhizoma alismatis  Blood-lipid lowering effective components  Orthogonal test  Extraction technic
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