| 正交试验法优选肝炎康胶囊的水煎提取制备工艺 |
| |
| 引用本文： | 李军民,王娟弟,秦龙,李平,李玉民,张岭漪.正交试验法优选肝炎康胶囊的水煎提取制备工艺[J].中国药师,2014(10):1662-1665. |
| |
| 作者姓名： | 李军民 王娟弟 秦龙 李平 李玉民 张岭漪 |
| |
| 作者单位： | 兰州大学第二医院 兰州 730030；;兰州大学第二医院 兰州 730030；兰州大学药学院;兰州大学第二医院;兰州大学第二医院；甘肃省消化系肿瘤重点实验室；;兰州大学第二医院；甘肃省消化系肿瘤重点实验室；;兰州大学第二医院 |
| |
| 基金项目： | 甘肃省科技计划项目(编号:145RJZA207);兰州大学第二医院院内中医药科研项目（编号:YJzy2013-26） |
| |
| 摘 要： | 目的：优选肝炎康胶囊的水煎提取制备工艺。方法：采用正交试验L9（34）法,以浸膏率和大黄素含量作为考察指标,优选肝炎康胶囊的最佳水煎提取制备工艺。结果：影响水煎提取工艺的因素次序依次为：提取次数（ B）〉提取时间（ A）〉加水倍量（ C）。最佳制备工艺条件为A3 B3 C2,即处方药材加10倍量的水、煎煮提取3次、每次2 h。结论：水煎提取制备工艺合理可行,可用于实际配制。
|
| 关 键 词： | 肝炎康胶囊 正交试验 水煎提取 大黄素 |
| 收稿时间： | 2014/3/21 0:00:00 |
| 修稿时间： | 2014/6/16 0:00:00 |
Optimization of Water Decocting Extraction Procedures for Ganyankang Capsules with Orthogonal Design |
| |
| Li Junmin,Wang Juandi,Qin Long,Li Ping,Li Yumin and Zhang Lingyi.Optimization of Water Decocting Extraction Procedures for Ganyankang Capsules with Orthogonal Design[J].China Pharmacist,2014(10):1662-1665. |
| |
| Authors: | Li Junmin Wang Juandi Qin Long Li Ping Li Yumin and Zhang Lingyi |
| |
| Institution: | Lanzhou University the Second Hospital, Lanzhou 730030, China;;Lanzhou University the Second Hospital, Lanzhou 730030, China;Pharmacy College of Lanzhou University;Lanzhou University the Second Hospital;Lanzhou University the Second Hospital; Key Laboratory of Digestive System Tumors;;Lanzhou University the Second Hospital; Key Laboratory of Digestive System Tumors;;Lanzhou University the Second Hospital |
| |
| Abstract: | ABSTRACT Objective: To optimize the water decocting extraction procedures for Ganyangkang capsules by orthogonal design. Methods: Using the extraction yield and emodin content as the indices, the optimal extraction conditions for Ganyankang capsules were studied by L9(34) orthogonal test. Results: The influencing order of the factors was B>A>C (A: extracting time, B: extracting duration, C: added water volume). The optimal preparation conditions were A3B3C2 , i.e. adding 10 fold water, decocting extracting 3 times with 2 hours each time.Conclusion:The optimum water decocting extraction procedures is rational and feasible. It can be used in the real preparation. |
| |
| Keywords: | Ganyankang capsules Orthogonal design test Water decocting extraction Emodin |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《中国药师》浏览原始摘要信息 |
| 点击此处可从《中国药师》下载免费的PDF全文 |
