徐州市2型糖尿病危险因素的病例对照研究

目的 筛选徐州市２型糖尿病的主要危险因素，为当地２型糖尿病的综合预防和干预提供科学依据。方法 采用频数匹配病例对照研究方法，随机选择徐州市２型糖尿病新诊断病例１８５例、医院对照２０１例和人群对照１９７例，对研究因素进行单因素和多因素非条件ｌｏｇｉｓｔｉｃ回归分析。结果 腰臀比大（ＯＲ＝２．３０）、经常性牛奶摄入（ＯＲ＝２．１９）、Ａ型性格（ＯＲ＝２．６５）、容易激动（ＯＲ＝１．８６）、高血压（ＯＲ

A case - control study of the risk factors of type 2 diabetes mellitus in Xuzhou City

Objective To recognize the main risk factors and provide evidence for prevention and intervention of type 2 diabetes mellitus.Methods A frequency matched case-control study based on hospital involving 185 new diagnosed type 2 diabetes mellitus cases and 201 control cases without type 2 diabetes mellitus was carried out in Xuzhou City,Jiangsu Province.In addition,197 healthy people in this district were also randomly selected as controls.The relationship between risk factors and type 2 diabetes mellitus was analyzed by nonconditional univariate and multivariate logistic regression on the Statistical Package for the Social Sciences(SPSS)for Windows,release 8 0.Results WHR(OR=3 07),family history of diabetes mellitus(O=2 65),high staple food intake(OR=3 45),usually sweet food intake(OR=2 73),high meat intake(OR=2 30),usually milk intake(OR=2 19),type A behavior(OR=2 65),easy to stir(OR=1 86),hypertension(OR=2 71)and number of pregnancies(OR=2 75)were significantly associated with type 2 diabetes mellitus after adjustment for all other risk factors.Occupational physical activity(OR=0 39 for light degree)and leisure time physical activity(OR=0 36 for occasionally and 0 44 forusually)were inversely associated with type 2 diabetes mellitus.Conclusion The results indicated that obesity,dietary factors(contain high total energy,high dietary fat and high glycemic load),physical inactivity,family history of diabetes mellitus,psychological factors,hypertension and number of pregnancies might be main risk factors of type 2 diabetes mellitus in Xuzhou city.Healthy life style intervention involving reasonable diet,persist in physical activity,weight controlling and psychological training may provide an effective program for prevention of type 2 diabetes mellitus.