| 宫颈癌术后不同放疗技术剂量学比较研究 |
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| 引用本文： | 张玉海,李月敏,夏火生,韩守云,李萍,刘志晨.宫颈癌术后不同放疗技术剂量学比较研究[J].中国医学物理学杂志,2010,27(1):1583-1587. |
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| 作者姓名： | 张玉海 李月敏 夏火生 韩守云 李萍 刘志晨 |
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| 作者单位： | 解放军第三零九医院放疗科,北京,100091 |
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| 摘 要： | 目的:比较研究宫颈癌术后调强放疗(IMRT)和常规四野(4F)或二野(2F)放疗时靶区及其周围危及器官受照剂量的差异。方法:随机选择6例宫颈癌术后患者,进行CT扫描、靶区和危及器官的勾画,用三维治疗计划系统进行常规4F、常规2F和IMRT计划设计,并对结果进行比较分析。结果:PTV适形度,IMRT计划优于常规4F计划,P=0.015,常规4F计划优于常规2F计划,P=0.043,差异具有统计学意义(P0.05)。与常规计划4F或2F相比,IMRT计划的膀胱50%体积受照剂量平均下降了25.8%和27.5%,直肠50%体积受照剂量平均下降了12%和14.3%,小肠50%体积受照剂量平均下降了36.5%和50%,而左、右股骨头和髂骨的差异无统计学意义。结论:在宫颈癌术后放疗中,IMRT技术较常规放疗技术有剂量学方面的优越性。
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| 关 键 词： | 宫颈癌 调强 三维治疗计划 |
Dosimetric Study of the Different Radiotherapy Ways for Postoperative Patients with Cervical Carcinoma |
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| ZHANG Yu-hai,LI Yue-min,XIA Huo-sheng,HAN Shou-yun,LI Ping,LIU Zhi-chen.Dosimetric Study of the Different Radiotherapy Ways for Postoperative Patients with Cervical Carcinoma[J].Chinese Journal of Medical Physics,2010,27(1):1583-1587. |
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| Authors: | ZHANG Yu-hai LI Yue-min XIA Huo-sheng HAN Shou-yun LI Ping LIU Zhi-chen |
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| Institution: | ZHANG Yu-hai,LI Yue-min,XIA Huo-sheng,HAN Shou-yun,LI Ping,LIU Zhi-chen(Department of Radiation Oncology,the 309th Hospital of PLA,Beijing 100091,China) |
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| Abstract: | Objective:To compare the dosimetric differences of the planning target volume(PTV)and the organs at risk(OAR)for postoperative patients with cervical cancer on intensity-modulated radiotherapy(IMRT)and conventional 4 fields(4F)or 2 fields(2F)radiotherapy.Methods:Six postoperative patients with cervical cancer were chosen randomly.The next steps were CT scan,PTV and OAR contouring.The treatment protocols were designed into conventional 4F,2F and IMRT by TPS.Finally,the dose distribution and DVH were compared... |
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| Keywords: | cervical cancer Intensity-modulated 3D treatment planning |
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