| 自制声学造影剂经静脉声学造影评价肾血流灌注的实验研究 |
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| 引用本文： | 郭文彬,张楠,张蕾,朱梅,梁皓,李文强,徐景涛.自制声学造影剂经静脉声学造影评价肾血流灌注的实验研究[J].医学影像学杂志,2005,15(7):593-595. |
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| 作者姓名： | 郭文彬 张楠 张蕾 朱梅 梁皓 李文强 徐景涛 |
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| 作者单位： | 山东大学,山东省立医院超声诊疗中心,山东,济南,250021 |
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| 摘 要： | 目的:探讨应用自制声学造影剂经静脉声学造影评价肾血流灌注的可行性。方法:应用自制声学造影剂为10只新西兰兔行经静脉肾脏声学造影,观察造影前、后肾脏二维超声图像,描绘肾皮质时间-强度曲线,测定峰值视频强度、基础视频强度、峰值-基础视频强度差及造影剂持续时间等参数。结果:造影后肾脏二维超声图像较造影前明显增强,肾皮质峰值视频强度与造影前(基础)视频强度有显著性差异(P<0.001)。结论:经静脉声学造影可以清楚地的观察到肾脏血流灌注的动态变化,能够对肾脏血流灌注作出定量评价。
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| 关 键 词： | 肾脏 血流灌注 声学造影剂 兔 |
| 文章编号： | 1006-9011(2005)07-0593-03 |
| 收稿时间： | 2005-03-07 |
| 修稿时间： | 2005年3月7日 |
An experimental study of assessing kidney perfusion by contrast sonography intravenously with a self-made contrast agent |
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| Guo WenBin;Zhang Nan;Zhang Lei;Zhu Mei;Liang Hao;Li WenJiang;Xu JingTao.An experimental study of assessing kidney perfusion by contrast sonography intravenously with a self-made contrast agent[J].Journal of Medical Imaging,2005,15(7):593-595. |
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| Authors: | Guo WenBin;Zhang Nan;Zhang Lei;Zhu Mei;Liang Hao;Li WenJiang;Xu JingTao |
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| Abstract: | Objective:To investigate the feasibility of renal perfusion by contrast sonography intravenously with a self-made contrast agent.Methods:A total of 10 New Zealand rabbits injected the self-made contrast agent were imaged with contrast sonography.2-D renal grey-scale imagings were observed before and after injection.A time-intensity curve was derived from renal cortical.Then the parameters,such as peak video intensity,basic video intensity,difference between peak intensity and basic intensity and the enhancement time were measured.Results:2-D renal grey scale imagings and renal cortical peak intensity were enhanced obviously after administration (P<0.001).Conclusion:Contrast sonography intravenously can observe the dynamic changes of renal blood perfusion and evaluate renal perfusion quantitively. |
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| Keywords: | Kidney Blood flow perfusion Ultrasonic contrast agent Rabbit |
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