129例住院肺血栓栓塞症患者栓塞面积与基础疾病相关性的分析

目的探讨肺血栓栓塞症（PTE）患者的栓塞面积大小与合并的基础疾病的相关性。方法收集2002年1月～2007年8月于我院住院治疗的PTE患者的临床资料，着重分析栓塞面积和合并的基础疾病，对影响栓塞面积的因子进行单因素和多因素相关分析。结果50～70岁为PTE的发病高峰年龄段，女性50岁以后发病要高于男性。PTE患者合并的基础疾病依次为：高血压（HBP）（58．91％），深静脉血栓形成（DVT）（47．29％），高脂血症（30．10％），慢性阻塞性肺疾病（COPD）（21．71％），冠心病（CHD）（20．93％），房颤（AF）（10．85％）等。56．59％的PTE患者合并2个以上基础疾病，合并基础疾病种类的多少与PTE栓塞面积的大小无相关性。单因素Х^2检验显示年龄（≤40岁、≥71岁）、近期手术、骨折病史，AF及DVT与大面积VIE的发生相关（P〈0．05）。多因素非条件Logistic回归分析显示，AF及DVT是大面积PTE的独立危险因素（P〈0．05）。结论年龄（≤40岁、≥71岁）、近期手术、骨折病史，AF及DVT与大面积PTE的发生相关，AF及DVT是大面积PTE的独立危险因素。

The correlation analysis of embolism area and basis diseases in patients with pulmonary thromboembolism

Objective To evaluate the correlation of embolism area and basis diseases in patients with pulmonary thromboembolism(PTE).Methods 129 patients with PTE admitted and treated in our department from 2002 to 2007 were retrospectively reviewed.Close attention was paid to embolism area and basis diseases.Influencing factors were extrapolated with univariate analysis and then multivariate analysis.Results Among the 129 patients,the peak period of age was 50~70 years old,the numbers of female were higer than that o...