小青龙贴中挥发油的提取工艺研究

目的优选小青龙贴中挥发油的最佳提取工艺条件。方法采用L9（34）正交试验方法,以得油率为考察指标,考察加水量、浸泡时间和提取时间三个因素对小青龙贴中得油率的影响。结果提取时间和浸泡时间对提取挥发油的影响最大,最有显著性意义,加水量对结果的影响较小。结合实际生产,最终确定小青龙贴中挥发油的提取工艺为：药材加8倍量水,浸泡1 h,水蒸气蒸馏6h。结论验证试验中三批小青龙贴得油率稳定,所优选的挥发油提取工艺简单、稳定、可行,适用于工业化大生产。

Study on the Extraction Process of Volatile Oil in Xiaoqinglong Plaster

Objective To optimize the best conditions of the extraction process of volatile oil in xiaoqinglong plaster.Methods L9（34）orthogonal test was adopted.The extraction rate of volatile oil was taken as the observation index.It was to observe the impacts of water amount,soak time and extraction time on the extraction rate of volatile ole in xiaoqinglong plaster.Results The extraction and soak time brought the best impact on the extraction of volatile oil,presenting the best significance.The water volume impacted less on the results.In consideration with the actual production,the final decision of the extraction process of volatile oil in xiaoqinglong plaster was：adding water 8 times as the weight of herbal materials,soaking for 1 h,steam distillation for 6 h.Conclusion In the verification test,the extraction rate of xiaoqinglong plaster of 3 batches is stable;the optimized extraction process of volatile oil is simple,stable and feasible.This process is suitable to be applied in the industrialized production.