原发性中枢神经系统恶性淋巴瘤MR表现分析

目的探讨原发性中枢神经系统恶性淋巴瘤（PCNSML）临床与影像学表现特点，提高本病的影像诊断水平。方法收集经手术、病理和免疫组化证实，资料齐全的颅内恶性非霍杰金淋巴瘤18例，回顾性分析其临床和MR表现。结果临床主要症状为头痛、恶心、偏瘫、肢体麻痹、视觉障碍等。18例患者单发肿瘤13例，多发肿瘤5例，肿瘤常常位于脑表面或近中线部位，T1WI呈略低或等信号，T2WI为低、等或略高信号，增强扫描病灶为明显均匀或不均匀强化，多呈“类圆形”或“团块状”。所有病灶都有占位效应，水肿程度不一。结论原发性中枢神经系统恶性淋巴瘤影像表现多样，但具有一定特征，MR扫描有助于该病变的诊断。

MRI Analysis of Primary Central Nervous System Malignant Lymphoma

Objective To explore the appearances of CT and MR with primary intracranial malignant lymphoma,in order to heighten the level of image diagnostics. Methods The clinical manifestations and findings of CT and MR1 were analyzed retrospectively in 18 patients with primary intraeranial malignant non-Hodgkin lymphoma proved by surgery,pathology and immunohistochemistry. Results The chief clin- ical manifestations were headache, nausea, hemiparesis, cerebellar signs, cranial nerve palsies, and visual disturbances. Most lesions were locat- ed near the surface or middle line of cerebrum. Slightly hypointense or isointense on TiWI,and sligtly hypointense or isointnse or slightly hy- perintense on T2WI, and homogeneous or inhomogeneous Gd-DTPA enhancement presented in most of the tumors, like＂round＂or＂clump＂. Mass effect and various edema surrounding the lesion can be seen in all the cases. Conclusion Primary intracranial malignant lymphoma has various imaging appearances, and there are the characteristic features. MR are helpful in diagnosis which can provide important information for therapeutic planning.