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异体脱钙骨基质骨粒复合骨水泥骨缺损修复材料结构特征及生物力学性能
引用本文:周勇,范清宇,蔡和平.异体脱钙骨基质骨粒复合骨水泥骨缺损修复材料结构特征及生物力学性能[J].中国组织工程研究与临床康复,2003,7(4):666-667.
作者姓名:周勇  范清宇  蔡和平
作者单位:Department of Orthopaedics,Tangdu Hospital,Fourth Military Medical University,Department of Orthopaedics,Tangdu Hospital,Fourth Military Medical University,The Research Institution for Strength of Metals Xi'an 710038,Shannxi Province,China,Xi'an 710038,Shannxi Province,China,Xi'an JiaoTong Univer sity,Xi'an 710000,Shannxi Province,China
摘    要:INTRODUCTIONAsthematerialstorepairthebonedefect,bonecementandde-calcifiedbonematrixareusuallyusedinclinic.Forresearchingthematerialwhichhasthecapabilityofboneinductionandbiome-chanicalstrength,wedesignedthecompoundbiomedicalmaterialimpregnatedthedecalcifiedbonematrixwithbonecementandanalyzedit'sconstructiveandbiomechanicalproperties.MATERIALSANDMETHODSPreparationofDBMparticlesAccordingtotheUrist'smethods1],thecortexboneseliminatedthesofttissueandmarrowwerebrokenintopie…


Constructive and biomechanical properties of material of decalcified bone matrix impregnated with bone cement
Zhou Yong,Fan Qingyu.Constructive and biomechanical properties of material of decalcified bone matrix impregnated with bone cement[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2003,7(4):666-667.
Authors:Zhou Yong  Fan Qingyu
Institution:1. Department of Orthopaedics, Tangdu Hospital,Fourth Military Medical University, Xi' an 710038, Shannxi Province,China
2. The Research Institution for Strength of Metals, Xi' an JiaoTong University, Xi'an 710000, Shannxi Province, China
Abstract:AIM: To analyze constructive and biomechanical properties of different quality ratio material impregnated decalcified bone matrix (DBM) with bone cement (BC) . METHODS: The DBM particles and the materials impregnated 0 rmg/g, 300 mg/g and 400 mg/g maas ratio DBM particles with BC were made according to the methods of Urist et al. The compound material constructions were observed by scanning electron microscope and the biomechanical properties were measured by Instron mechanics testing-machine. RESULTS: The DBM particles with irregular gaps existing within interspace were connected with BC by the multipoint mode in the compound material. The ultimate compressive strength were 0 mg/g DBM in (59.3 ±2.2) MPa, 300 mg/g in (27.1 ±1.8) MPa, 400 mg/g in (19.3±1.6) MPa. The ultimate bending strength were 0 mg/g in (54.3±3.7) MPa, 300 mg/g in (18.5±1.1) MPa, 400 mg/g in (13.3±1.4) MPa. CONCLUSION: The materials of DBM impregnated with BC had perfect plastic property with much more irregular gaps existing within interspace. The materials could provide abundant biomechanical support.
Keywords:osteogenesis  bone matrix  bone morphogenetic proteins  biocompatib le materials  mice
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