女性精神分裂症患者认知功能损害危险因素

目的探讨女性精神分裂症患者认知功能损害的危险因素,提供治疗认知功能损害的依据。方法采用自编调查表、阳性与阴性症状量表(PANSS)、简易智能精神状态量表(MMSE)对100例女性精神分裂症患者调查,认知功能损害危险因素采用Logistic回归分析。结果认知功能损害发生率为72%,阴性症状是认知功能损害的危险因素(B=0.151,Exp(B)=1.163),文化水平是认知功能损害的保护因素(B=-0.282,Exp(B)=0.754)。结论阴性症状越重认知功能损害危险度越高,文化水平越高认知功能损害危险度越低。

Risk Factors of Cognitive Impairment in Female Patients with Schizophrenia

Objective To explore risk factors of cognitive impairment in female patients with schizophrenia,and provide some basis for treatment of cognitive impairment.Methods A total of 100 female patients with schizophrenia were investigated by self-made questionnaire,the positive and negative symptom scale(PANSS),mini-mental state examination(MMSE),the risk factors for cognitive impairment was used logistic regression analysis.Results 72% of female patients with schizophrenia had cognitive impairment,negative symptoms was a risk factor for cognitive impairment(B=0.151,Exp(B)=1.163),cultural level was a protective factor for cognitive impairment(B=-0.282,Exp(B)=0.754).Conclusion The more severe the negative symptoms,the higher the risk of cognitive impairment.The higher the cultural level,the lower the risk of cognitive impairment.