Primary adult T-cell lymphoma of the breast. |
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| Authors: | M Kosaka N Tsuchihashi M Takishita Y Miyamoto K Okagawa T Gotoh S Saito M Komaki T Morimoto T Sano |
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| Affiliation: | First Department of Internal Medicine, University of Tokushima, Japan. |
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| Abstract: | A case of primary adult T-cell lymphoma (ATL) of the breast is described. A 69-year-old woman presented with a painless, rapidly growing lump in her left breast. Staging procedures demonstrated no sign of generalized disease. Following a Patey's mastectomy, 10 courses of adjuvant chemotherapy (CHOP) were successfully administered. The light microscopic, immunohistochemical and molecular genetic analyses of the surgical specimen revealed a primary ATL. Seropositive mothers who breast-feed their children may facilitate the accumulation of T cells carrying HTLV-I in their breasts and thereby increase their risks of developing breast ATL. |
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