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利福平对膀胱癌术后灌注BCG所致不良反应的疗效评价
引用本文:王万用,程伟,张雄,黄捷.利福平对膀胱癌术后灌注BCG所致不良反应的疗效评价[J].重庆医学,2008,37(9):950-951.
作者姓名:王万用  程伟  张雄  黄捷
作者单位:重庆市第九人民医院泌尿外科,400700;重庆市第九人民医院泌尿外科,400700;重庆市第九人民医院泌尿外科,400700;重庆市第九人民医院泌尿外科,400700
摘    要:目的探讨利福平防治膀胱癌术后灌注卡介苗(BCG)所致不良反应的疗效。方法对67例膀胱癌患者术后行BCG灌注,随机分成两组,对照组和利福平治疗组,比较两组BCG灌注后各种不良反应发生率的情况。结果治疗组灌注后血尿、发热和膀胱刺激症状发生率明显低于对照组,差异有统计学意义(P<0.01)。结论应用利福平可有效预防和减轻膀胱癌患者术后灌注BCG的不良反应。

关 键 词:膀胱癌  利福平  卡介苗
文章编号:1671-8348(2008)09-0950-02
修稿时间:2007年9月13日

Evaluation the curative effect of Rifampicin on adverse reaction of BCG after carcinoma of bladder operation
WANG Wan-yong,CHENG Wei,ZHANG Xiong,et al..Evaluation the curative effect of Rifampicin on adverse reaction of BCG after carcinoma of bladder operation[J].Chongqing Medical Journal,2008,37(9):950-951.
Authors:WANG Wan-yong  CHENG Wei  ZHANG Xiong  
Abstract:Objective To investigate the curative effect of Rifampicin on adverse reaction of Bacillus Calmette-Guerin(BCG) after carcinoma of bladder operation.Methods Sixty-seven postoperative patients with bladder cancer were divided into two groups to receive intravesical instillation of BCG,to compare the incidence rate of adverse reaction of the control group and the treatment group(by Rifampicin).Results The incidence rate of adverse reaction of the treatment group reduced significantly compared with control group(P<0.01).Conclusion Rifampicin can prevent and relieve effectively the adverse reaction of intravesical instillation of BCG after bladder cancer operation.
Keywords:bladder cancer  rifampicin  bacillus calmette-guerin
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