Universit?t-Kinderklinik, Moorenstrasse 5, D-40225 Düsseldorf, Germany, DE Department of Medicine, New York University, N.Y., USA, US
Abstract:
Some recent publications indicate that inherited disorders can ameliorate or possibly disappear if mutations responsible for
the disease revert to normal. This review tries to summarize our current knowledge about reverse mutations as this information
may be of special interest for attempts at somatic gene therapy.
Received: 14 July 1997 / Accepted: 2 March 1998