Dexmedetomidine in a Child with Methylphenidate Intoxication |
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Authors: | Dayanand N. Bagdure Girija R. Bhoite Pamela D Reiter Emily L. Dobyns |
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Affiliation: | 1. Pediatric Intensive Care Unit, Section of Critical Care Medicine, Children’s Hospital Colorado, 13123 East 17th Ave, Mail Stop 8414, Aurora, CO, 80045, USA 2. Union Memorial Hospital, Baltimore, MD, USA 3. Department of Pharmacy, Center for Pediatric Medicine, Children’s Hospital, Colorado, Aurora, CO, USA
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Abstract: | Methylphenidate intoxication, due to accidental ingestion, is a common occurrence in pediatrics. Symptoms of extreme agitation are typically controlled with benzodiazepines or barbiturates. There is, however, a legitimate risk of mechanical ventilation due to respiratory depression with increasing doses of benzodiazepines. The authors describe a case of 7-y-old girl with methylphenidate toxicity where dexmedetomidine was successfully used to manage agitation and cardiovascular stimulation without respiratory compromise. |
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