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Red Yeast Rice Increases Excretion of Bile Acids in Hamsters
Authors:KA-YING MA  ZE-SHENG ZHANG  SHU-XIN ZHAO  QI CHANG  YIN-MEI WONG  SAI YING VENUS YEUNG  YU HUANG   ZHEN-YU CHEN   Food    Nutritional Sciences Program
Affiliation:KA-YING MA,ZE-SHENG ZHANG,SHU-XIN ZHAO,QI CHANG,YIN-MEI WONG,SAI YING VENUS YEUNG,YU HUANG,AND ZHEN-YU CHEN,1 Food and Nutritional Sciences Program,Department of Biochemistry,The Chinese University of Hong Kong,Shatin,New Territories,Hong Kong,China,Faculty of Food Engineering & Biotechnology,Tianjin University of Science and Technology,Tianjin 300457,Institute of Medicinal Plant Development,Chinese Academy of Medical Science & Peking Union Medical College,Beijing 100193,De...
Abstract:Objective To investigate the hypocholesterolemic activity of red yeast rice (RYR) and its underlying mechanism. Methods Three groups of hamsters were fed either the control diet or one of the two experimental diets containing by weight 0.1% RYR (0.1RYR) or 0.3% RYR (0.3RYR). Blood (0.5 mL) was collected from the retro-orbital sinus into a heparinized capillary tube at the end of week 0, 3, and 6. Plasma lipoproteins were measured using enzymatic kits, while fecal neutral and acidic sterols were quantified u...
Keywords:Bile acid  Cholesterol  Monacolin  Red yeast rice  Triacylglcerols  
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