生长抑素在术后粘连性肠梗阻治疗中的应用体会

目的探讨生长抑素在治疗术后粘连性肠梗阻中的作用。方法将53例术后粘连性肠梗阻患者分为治疗组（28例）及对照组（25例）。对照组采用常规治疗,包括胃肠减压、灌肠、补液及抗感染治疗等;治疗组在常规治疗的基础上加用奥曲肽（生长抑素类似物）0.2mg ih,q8h,治疗72h,观察两组患者腹痛、腹胀症状变化,肛门恢复排气排便情况,胃肠减压量,住院时间及中转手术率的情况。结果治疗组较对照组腹痛腹胀缓解率明显改善,恢复排气时间明显缩短和中转手术率显著降低,胃肠减压量显著减少。结论在术后粘连性肠梗阻的常规治疗基础上加生长抑素,可改善患者临床症状,降低手术中转率,改善患者生活质量。

Somatostatin in the treatment of adhesive intestinal obstruction after the application of experience

Objective To investigate the somatostatin in the treatment of postoperative adhesive intestinal obstruction in the role.Methods 53 cases of postoperative adhesive intestinal obstruction were divided into treatment group(28 patients) and control group(25 cases).Control group with conventional treatment,including decompression,enemas,rehydration and anti-infection treatment;treatment group on the basis of conventional therapy plus octreotide(somatostatin analogue) 0.2mg ih,q8h,treatment of 72h,observed in patients with abdominal pain,bloating symptoms change,restore exhaust anal defecation,gastrointestinal decompression volume,length of stay and transfer rates of surgery.Results The treatment group than the control group response rate was significantly improved abdominal pain and distension,flatus significantly shorter and significantly lower rates of surgical intervention,decompression was significantly reduced.Conclusion Of adhesive intestinal obstruction after conventional treatment based on somatostatin,can improve clinical symptoms,reduce the rate of transit operations,improve patient quality of life.