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茶叶对黄曲霉毒素B_1-DNA加合物生成的影响
引用本文:朱家琦 王颖. 茶叶对黄曲霉毒素B_1-DNA加合物生成的影响[J]. 卫生研究, 1993, 22(1): 27-30
作者姓名:朱家琦 王颖
作者单位:中国预防医学科学院营养与食品卫生研究所 北京100050
摘    要:本研究在体外实验条件下,测定了乌龙茶水等12种茶样对黄曲霉毒素 B_1(AFB_1)-DNA加合物生成的影响。结果表明,受试样品在高浓度下均有明显抑制AFB_1-DNA加合物生成的作用,随着浓度下降,抑制作用亦随之降低,有明显的剂量-反应关系。本实验结果提示,茶叶对AFB_1的致癌性可能具有一定的抑制作用。

关 键 词:茶叶  黄曲霉毒素B_1   DNA加合物

Effect of tea on the formation of DNA adduct by aflatoxin B_1
Zhu Jiaqi,Wang Ying,Liu Zeqin. Effect of tea on the formation of DNA adduct by aflatoxin B_1[J]. Journal of hygiene research, 1993, 22(1): 27-30
Authors:Zhu Jiaqi  Wang Ying  Liu Zeqin
Abstract:Twelve tea samples have been tested for the effect on the formationof DNA adduct by aflatoxin B_1 in vitro.It was found that all of thesesamples have significant inhibitory effect on DNA adduct formation by aflatoxin B_1 at the high concentration and the effect tends to reduce asthe concentration lowers. The response was in a dose-dependent manner.It was suggested that tea may have potential anti carcinogenic activityagainst aflatoxin B_1.
Keywords:tea   aflatoxin B_1   DNA adduct
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