| 血小板活化因子及其受体拮抗剂的研究进展 |
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| 引用本文： | 袁奇,张小华,乔延江.血小板活化因子及其受体拮抗剂的研究进展[J].中华中医药杂志,2011(7):1568-1571. |
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| 作者姓名： | 袁奇 张小华 乔延江 |
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| 作者单位： | 北京中医药大学; |
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| 摘 要： | 目的:综述血小板活化因子(PAF)及其受体拮抗剂的研究进展。方法:根据已报道的介绍PAF及其受体拮抗剂的相关文献,介绍PAF及其拮抗剂的研究进展。结果:从PAF的结构、作用机制、PAF受体拮抗剂类型等方面介绍了PAF及其拮抗剂的研究进展。结论:PAF是具有广泛生物活性的磷脂细胞因子,参与人体多种生理、病理过程。而PAF受体拮抗剂可以拮抗PAF引起的病理反应。对PAF及其受体拮抗剂的研究对人类疾病的治疗有巨大意义。
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| 关 键 词： | 血小板活化因子 生物活性 化学结构 作用机制 PAF受体拮抗剂 |
Research advances in PAF and its receptor antagonist |
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| YUAN Qi,ZHANG Xiao-hua,QIAO Yan-jiang.Research advances in PAF and its receptor antagonist[J].China Journal of Traditional Chinese Medicine and Pharmacy,2011(7):1568-1571. |
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| Authors: | YUAN Qi ZHANG Xiao-hua QIAO Yan-jiang |
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| Institution: | YUAN Qi,ZHANG Xiao-hua,QIAO Yan-jiang(Beijing University of Chinese Medicine,Beijing 100102,China) |
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| Abstract: | Objective: Reviewing the resent developments in research of platelet activating factor(PAF) and its receptor antagonist.Methods: Describing the current researches about PAF and its receptor antagonist according to the related literatures.Results: Summarizing the resent research results about PAF and its receptor antagonist from the aspects of chemical structure,action mechanism and types of receptor antagonist.Conclusion: PAF is a Phospholipids Cell Factor which has very wide biological activity.It particip... |
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| Keywords: | Platelet activating factor Biological activity Chemical structure Action mechanism PAF receptor antagonist |
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