| 血瘀证目征与血管内皮细胞损伤的关系 |
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| 引用本文： | 黄敏,谢建祥,吴锐,黄国栋,王善超,李国贤.血瘀证目征与血管内皮细胞损伤的关系[J].中华中医药杂志,2011(4):781-784. |
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| 作者姓名： | 黄敏 谢建祥 吴锐 黄国栋 王善超 李国贤 |
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| 作者单位： | 江西省儿童医院;南昌大学第一附属医院;江西省中医院; |
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| 基金项目： | 国家自然科学基金(No.30960473/C190106)~~ |
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| 摘 要： | 目的:探讨血瘀证目征与血管内皮细胞损伤的关系。方法:将54只新西兰大白兔按随机分组法分为6组,分别为气虚血瘀组、气滞血瘀组、寒凝血瘀组、热毒血瘀组、外伤血瘀组、正常对照组。比较各组血瘀证目征积分,同时观测各组血清中vWF、ET-1水平的变化。结果:造模前各组血瘀证目征积分无显著差异:造模后各治疗组与对照组相比均有极显著差异(P<0.01):经补阳还王汤等中药2周治疗后,各治疗组与各自造模后相比均有极显著差异(P<0.01)。造模前各组血清ET-1,vWF的水平无显著差异,造模后血清ET-1,vWF水平各治疗组与对照组相比均有极显著差异(P<0.01),治疗后,各治疗组与各自造模后相比均有极显著差异(P<0.01)。结论:血瘀证目征是诊断血瘀证的有效方法,血瘀证目征与血管内皮细胞损伤有密切相关。
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| 关 键 词： | 血瘀证目征 血管内皮细胞 血管假血友病因子 肉皮素1 实验研究 |
Experimental study of relationship between the eye signs of blood stasis syndrome and the vascular endothelial cell injury |
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| HUANG Min,XIE Jian-xiang,WU Rui,HUANG Guo-dong,WANG Shan-chao,LI Guo-xian.Experimental study of relationship between the eye signs of blood stasis syndrome and the vascular endothelial cell injury[J].China Journal of Traditional Chinese Medicine and Pharmacy,2011(4):781-784. |
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| Authors: | HUANG Min XIE Jian-xiang WU Rui HUANG Guo-dong WANG Shan-chao LI Guo-xian |
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| Institution: | HUANG Min1,XIE Jian-xiang1,WU Rui2,HUANG Guo-dong2,WANG Shan-chao3,LI Guo-xian2(1Children,s Hospital of Jiangxi,Nanchang 330006,China,2The First Affiliated Hospital of Nanchang University,3TCM Hospital of Jiangxi Province,China) |
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| Abstract: | Objective:To investigation the relationship between the eye signs of blood stasis syndrome and the vascular endothelial cell injury.Methods:In this study a sample of 54 rabbits randomly divided into 6 blood stasis groups:qi deficiency group,qi stagnation group,cold coagulation group,heat-toxicity group,trauma group and normal control group.Comparison of the Eye Signs scores of blood stasis syndrome in each group,while observing the changes of vWF,ET-1 levels in serum.Results:There was no significant differe... |
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| Keywords: | Eye signs of blood stasis syndrome Vascular endothelial cells vWF ET-1 Experimental study |
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