Role of ERK1/2 and vascular cell proliferation in cerebral vasospasm after experimental subarachnoid hemorrhage |
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Authors: | Duo Chen Jian-Jun Chen Qiang Yin Jun-Hong Guan Yun-Hui Liu |
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Affiliation: | (1) Department of Neurosurgery, The Affiliated Shengjing Hospital of China Medical University, Shenyang, China |
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Abstract: | Background Although there are still some unresolved aspects, current research has revealed that vascular cell proliferation probably plays an important part in the pathological formation process of cerebral vasospasm. Using a “two-hemorrhage” model of subarachnoid hemorrhage (SAH), this study investigated the function of ERK1/2 and vascular wall cell proliferation in pathological development of cerebral vasospasm. |
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