Abstract: | The first clinical trials of praziquantel against Schistosoma japonicum infections in Japan were planned to assess tolerance only. Three double-blind studies against placebo involving a total of 51 patients were conducted with dosages of praziquantel of 1 × 20 mg/kg body weight, 2 × 20 mg/kg, 3 × 20 mg/kg given on one day. |