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| 石榴皮中鞣花酸的提取工艺研究 | |
| 引用本文： | 李海霞,王彩芳,张红岭,方晓燕,董保国.石榴皮中鞣花酸的提取工艺研究[J].中国医药导报,2008,5(24):50-51. |
| 作者姓名： | 李海霞 王彩芳 张红岭 方晓燕 董保国 |
| 作者单位： | 1. 郑州大学药学院,河南郑州,450051 2. 河南中医学院,河南郑州,450003 3. 郑州时代旗舰科技有限公司,河南郑州,450008 |
| 摘 要： | 目的：考察石榴皮中鞣花酸的提取工艺。方法：选用4因素3水平正交表L9（34），以薄层扫描法测定鞣花酸含量，考察4个因素（溶剂类型，提取时间，提取次数，溶剂用量）、3个水平对鞣花酸提取率的影响。结果：鞣花酸的最佳提取工艺为用1mol/L的盐酸水溶液、8倍量、回流提取60min、提取2次；结论：溶剂类型对鞣花酸的提取率影响最大，本研究确定的鞣花酸提取工艺合理、可行。 |
| 关 键 词： | 石榴皮 鞣花酸 提取工艺 正交试验 |
Study on extract technology of ellagic acid in the peels of Punica granatum |
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| LI Hai-xia,WANG Cai-fang,ZHANG Hong-ling,FANG Xiao-yan,DONG Bao-guo.Study on extract technology of ellagic acid in the peels of Punica granatum[J].China Medical Herald,2008,5(24):50-51. | |
| Authors: | LI Hai-xia WANG Cai-fang ZHANG Hong-ling FANG Xiao-yan DONG Bao-guo |
| Institution: | LI Hai-xia, WA NG Cai-fang, ZHA NG Hong-ling, FANG X iao-yan,DONG Bao-guo (1. College of Pharmacy, Zhengzhou University, Zhengzhou 450051 ,China;2. Henan College of Traditional Chinese Medicine,Zhengzhou 450003,China;3.Technology Limited Company of Zhengzhou Times Flagship, Zhengzhou 450008, China) |
| Abstract: | Objective:To investigate the extract technology of ellagic acid in the peels of Punica granatum. Methods:The thin layer scanning method was used to determine the content of ellagic acid. The orthogonal design with three levels of four factors (the solvent, the extracting time, the extracting times and the amount of solvent) was adopted, using ellagic acid as index to evaluate the results. Results: The best extracting condition for ellagic acid was to add 8 times amounts of the water solution of 1 mol/L hydrochloric acid, and to reflux for 60 min and extract twice. Conclusion: The solvent has the maximal influence to the dissolutions of ellagic acid. The extract technology of ellagic acid was feasible and reasonable. |
| Keywords: | Peels of Punica granatum Ellagic acid Extract technology Orthogonal test |
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