| 甲氨蝶呤辅助早孕药物流产的临床观察 |
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| 引用本文： | 李春梅. 甲氨蝶呤辅助早孕药物流产的临床观察[J]. 中国性科学, 2011, 20(5): 17-19. DOI: 10.3969/j.issn.1672-1993.2011.05.006 |
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| 作者姓名： | 李春梅 |
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| 作者单位： | 解放军520医院妇产科,四川,绵阳,621000 |
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| 摘 要： | 目的:探讨甲氨蝶呤辅助米非司酮配伍米索前列醇终止早孕的临床效果。方法:将264例妊娠34~49天妇女随机分成观察组与对照组,对照组采用米非司酮配伍米索前列醇进行药物流产,观察组额外加用甲氨蝶呤辅助药物流产,对两组药物流产成功率、孕囊2h内的排出率、阴道出血持续时间、尿HCG 10天内转阴情况进行比较。结果:观察组药物流产成功率、孕囊2h内的排出率优于对照组,差异有高度统计学意义(P<0.01);观察组阴道出血持续时间10天内干净与尿HCG 10天内转阴发生率较对照组高,差异有统计学意义(P<0.05);两组各种副反应发生率差异均无统计学意义(P>0.05)。结论:单次口服25mg甲氨喋呤片辅助早孕药物流产,可以明显提高流产成功率、缩短孕囊排出的时间,可以缩短阴道出血持续时间,药物副反应无明显增加。
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| 关 键 词： | 甲氨蝶呤 米非司酮 米索前列醇 药物流产 |
Clinical observation of methotrexate auxiliary medical abortion of early pregnancy |
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| LI Chunmei. Clinical observation of methotrexate auxiliary medical abortion of early pregnancy[J]. The Chinese Journal of Human Sexuality, 2011, 20(5): 17-19. DOI: 10.3969/j.issn.1672-1993.2011.05.006 |
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| Authors: | LI Chunmei |
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| Affiliation: | LI Chunmei Department of Obstetrics and Gynecology,520 Hospital of PLA,Sichuan Mianyang 621000,China |
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| Abstract: | Objectives: To study clinical effects of methotrexate auxiliary mifepristone and misoprostol to terminate early pregnancy.Methods: 264 patients 34~49 days pregnant women were randomly divided into observation group and control group.The control group were treated with mifepristone and misoprostol for medical abortion,the observation group extra auxiliary medical abortion with methotrexate,the two group success rate of medical abortion,pregnancy sac discharge rate of 2 hours,the duration of vaginal bleeding,... |
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| Keywords: | Methotrexate Mifepristone Misoprostol Medical abortion |
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