上海市3～14岁儿童哮喘危险因素病例对照研究

目的探讨上海市浦东新区3～14岁儿童哮喘的危险因素。方法选择2008年11月至2009年3月收治的哮喘儿童60例,1:1配对非哮喘儿童60例为对照组,采用单因素Logistic回归分析哮喘危险因素。结果父母哮喘史、儿童过敏史、家庭通风换气时间、家庭是否安装通风换气设备和儿童呼吸道感染情况是上海市浦东新区儿童哮喘的危险因素。结论儿童哮喘是环境因素和遗传因素共同作用诱导的复杂疾病,可以通过减少呼吸道感染和避免接触过敏原等方面进行儿童哮喘的防治。

A case control study on risk factors of asthma among children aged 3-14 in Shanghai

Objective To explore the risk factors of asthma among children aged 3 - 14 in Pudong New District of Shanghai.Methods 1:1 matched case- control study was adopted.65 cases and 65 age - sex - controls from the same hospital were investigated on the risk factors.Single logistic regression models were processed respectively.Results Family history of asthma,history of allergy,history of respiratory tract infection,duration of family ventilation,family ventilation device were the risk factors of children aged 3 - 14 in Pudong New District of Shanghai.Conclusion Children asthma is a multi - factorial complex disease,and the interaction of environmental and genetic risk factors play an important role in the onset of the disease.Thus,through the prevention of respiratory tract infections and reduction the allergen exposure,it is possible to prevent and cure children asthma.