高强度训练官兵血中胰岛素样生长因子-1变化及临床意义

目的了解高强度训练对受训人员血中胰岛素样生长因子-1的影响。方法于训练中期随机抽取阅兵集训（高强度训练）的30名官兵及相似的30名普通训练的官兵．抽血离心，取血清，测定血清中胰岛素样生长因子-1、细胞间黏附因子-1、去甲肾上腺素及超敏C反应蛋白的浓度。结果阅兵组训练组的胰岛素样生长因子-1浓度为（5．895±2．012）μg/L，明湿高于普通训练组（4．471±2．268）μg／L，P〈0．05]，阅兵组的去甲肾上腺素浓度为Ⅰ（173．320±101．156）pmol／L，明显高于普通训练组（46．422±27．785）pmol／L，P〈0．05]，阅兵组的细胞间黏附因子-1的浓度为（4．780±1．301）μg／L，明显高于普通训练组（2．842±0．630）μg／L，P〈0．05]，而阅兵组的超敏C反应蛋白（1．235±2．252）mg／L]同普通训练组（1．482±2．000）mg／L]间未见明显差异（P〉0．05）。结论高强度训练组血中胰岛素样生长因子-1明显高于普通训练组，这表明高强度训练中存在骨骼肌损伤和修复。

Insulin-like growth factor-1 level of the intensive drilling troops and the clinical significance thereof

Objective To investigate the effects of high intensity drilling on the insulin-like growth factor 1 （IGF-1） concentration in blood of the officers and men undergoing high-intensity drilling. Methods In the midterm of the drilling for parade in the National Day 2009, peripheral blood samples were collected from 30 officers and men undergoing intensive drilling and 30 officers and men undergoing routine drilling to examine the concentrations of IGF-1, noradrenaline （NA）, serum intercellular adhesion molecule 1 （sICAM-1）, and high sensitive C- reactive protein （hsCRP）. Results The concentration of IGF-1 （5.8953-2.012） ug/L] in the intensive drilling group was significantly higher than that （4.471±2.268） μ g/L] in the control group （P〈 0.05）. The concentration of NA （173.320±101.156） pmol/L] in the intensive drilling group was significantly higher than that （46.422±27.785） pmol/L] in the control group （P〈 0.0001）. The concentration of sICAM-1 （4.780± 1.301） μg/L] in the intensive drilling group was significantly higher than that （2.842±0.630） μg/L] in the control group （P〈 0.0001 ）. However. the concentration of hsCRP （1.235±2.2521 mg/L] in the intensive drilling group demonstrated no significantly difference with that （1.482±2.000） mg/ L] in the control group （P〉 0.05）. Conclusion The concentration of IGF-1 in the intensive drilling troops is higher than that in the control group. It suggests that there are injury and recovering of skeletal muscles in the intensive drilling troops.