儿科重症监护室下呼吸道感染常见病原菌分布及耐药分析

目的 探讨儿科重症监护室重症下呼吸道感染患儿痰液标本培养和药敏监测的意义.方法 回顾性分析1107例儿童重症监护室下呼吸道感染患儿痰液标本培养和药敏监测结果.结果 1107例标本共培养病原菌948株（85.64%）.其中G-菌616株（64.98%）中铜绿假单胞菌145株（15.30%）、肺炎克雷伯菌135株（14.24%）、鲍曼不动杆菌131株（13.82%）、大肠埃希菌89株（9.40%）;G＋菌129株（13.61%,主要以金黄色葡萄球菌为主）;真菌203株（21.41%,主要为白假丝酵母菌）.细菌主要敏感药物监测结果：G‘类为碳青霉烯类抗生素,G＋类为万古霉素.结论 重症患儿下呼吸道感染病原菌主要为G-菌,其次为G＋菌和真菌,感染菌对敏感抗生素具有高选择性,应根据药物敏感监测结果使用抗生素.

Analysis on the pathogenic bacteria distribution and drug resistance of the patients in PICU with lower respiratory tract infection

Objective To explore the significance of sample cultivation and drug resistance of the patients in PICU with severe lower respiratory tract specimens.Methods 1 107 pathogenic bacteria of lower respiratory tract samples collected were analyzed and the drug resistance was kept watch on.Results A total of 1107 samples were cultured into 948 strains of pathogens,with the positive rate of 85.64%,and 616 strains of Gram negative bacteria accounting for 64.98%,of which 145 strains of Pseudomonas aeruginosa(15.30%),Klebsiella pneumoniae 135(14.24%),Acinetobacter spp 131(13.82%),large intestine Egypt Greek bacteria 89(9.4%);Gram positive cocci 129(13.61%),the main pathogen was staphylococcus aureus and Fungi 203(21.41%),the main pathogen was candida albicans.Carbapenems was the most active antibiotics for gram negative bacill,and vancomycin for gram positive cocci.Conclusion Infectious bacteria have high selectivity to the sensitive antibiotics,and doctors should carefully use antibiotic according to the susceptibility test results in order to reduce hospital infection and the emergence and spread of resistant strains.