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越鞠丸联合帕罗西汀治疗抑郁发作的临床疗效观察
作者姓名:高丽丽  吴成翰  王谨敏
作者单位:福建中医药大学附属第二人民医院脑病科
基金项目:福建省自然科学基金项目(2020J01247);福建省卫健委中青年骨干人才培养项目(2019-ZQN-78)。
摘    要:目的 观察越鞠丸联合帕罗西汀治疗抑郁症的临床效果及安全性.方法 选取医院100例抑郁症患者为研究对象,按照随机数字法分为对照组和观察组两组,观察组给予越鞠丸组联合帕罗西汀治疗,对照组给予帕罗西汀治疗.观察两组的临床疗效及安全性.结果 治疗前两组汉密尔顿抑郁量表(Hamilton depression scale,HAM...

关 键 词:越鞠丸  帕罗西汀  抑郁症  汉密尔顿抑郁量表  贝克抑郁量表  临床疗效

Clinical Observation of Yueju Pill Combined With Paxil in the Treatment of Depressive Episode
Authors:GAO Lili  WU Chenghan  WANG Jinmin
Institution:(Deparment of Brain Disease,The Second Affiliated Hospital of Fujian Traditional Chinese Medical University,Fuzhou Fujian 350003,China)
Abstract:Objective To observe the clinical effect and safety of Yueju Pill combined with paroxetine in the treatment of depression.Methods A total of 100 patients with depression in our hospital were selected as the research object and divided into two groups according to the random number method,control group and observation group.The observation group was treated with Yueju Pill combined with paroxetine,and the control group was treated with paroxetine.The clinical efficacy and safety of the two groups were observed.Results There was no significant difference in Hamilton depression scale(HAMD)and Beck depression rating scale(BDI)scores between the two groups before treatment(P>0.05).After treatment,HAMD and BDI scores of the observation group were lower than those of the control group,the difference was statistically significant(P<0.05).The degree of adverse reactions in observation group was significantly lower than that in control group,the difference was statistically significant(P<0.05).Conclusion The combination of Yueju Pill and paroxetine has significant effect in the treatment of depression,and can significantly improve the patients5 depressive mood,and the degree of adverse reactions is mild.
Keywords:Yueju Pill  paroxetine  depression  Hamilton depression scale  Baker depression scale  clinical effect
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