实时剪切波弹性成像在前列腺癌诊断及风险分级中的应用价值

目的 探讨经直肠实时剪切波弹性成像技术(SWE)在前列腺癌(PCa)诊断及风险评估中的应用价值.方法 选取2015年6月至2020年12月因尿频或排尿困难等症状就诊于宝鸡市中心医院的349例患者,其在行前列腺穿刺活检前均接受了直肠SWE检查,在6个位置测量前列腺的杨氏模量,以测量结果的平均值作为前列腺标准化硬度,包括E...

Application value of real-time shear wave elastography in the diagnosis and risk classification of prostate cancer

Objective To explore the application value of transrectal real-time shear wave elastography(SWE) in the diagnosis and risk classification of prostate cancer(PCa).Methods A total of 349 patients admitted in Baoji central hospital from June 2015 to December 2020 due to frequent urination or dysuria were selected,and all underwent transrectal SWE examination before prostate biopsy.The Young’s modulus of the prostate was measured in six locations,the average of the measurement results was defined as the standardized stiffness of prostate gland,including Emax,Emean and Emin.The clinical data and standardized stiffness of patients with different nature of prostate disease were compared;the PCa patients were divided into low-risk,medium-risk and high-risk groups,and the standardized stiffness of prostate gland of each group were compared;the diagnostic efficacy of standardized stiffness of prostate gland for high-risk PCa was analyzed.Results The Emax,Emean and Emin of standardized stiffness of prostate gland in the malignant group were significantly higher than those in the benign group,and the differences were statistically significant(P<0.05).The Emax,Emean and Emin of standardized stiffness of prostate gland in the high-risk group were higher than those in the medium-risk and the low-risk groups,and the differences were statistically significant(P<0.05);there were no significant differences in Emax,Emean and Emin of standardized stiffness of prostate gland between the medium-risk and the low-risk groups(P>0.05).The AUC of Emax and Emean was greater than that of Emin,and the differences were statistically significant(P<0.05);there was no significant difference in AUC between Emax and Emean(P>0.05).Conclusion The standardized stiffness of prostate gland measured by SWE has certain reference value in the diagnosis of PCa,and it may be a simple and reliable ultrasonic imaging method for high-risk PCa detection.