脑卒中后抑郁合并认知功能障碍的磁共振灌注成像观察

目的:观察脑卒中后抑郁合并认知功能障碍的磁共振灌注成像,探讨脑卒中后抑郁症合并认知障碍的发病机制.方法:选取青岛大学附属医院2020年2月—2021年2月收治的90例脑卒中患者,根据疾病类型不同将患者分为卒中组和合并组各45例.卒中组为单纯卒中患者,合并组为脑卒中后抑郁合并认知功能障碍患者.两组均进行磁共振灌注(PWI...

Observation of magnetic resonance perfusion imaging of post-stroke depression combined with cognitive dysfunction

Objective To observe the magnetic resonance perfusion weighted imaging of post-stroke depression with cognitive impairment,and to explore the pathogenesis of post-stroke depression with cognitive impairment.Methods 90 cases of cerebral apoplexy patients treated in the affiliated hospital of Qingdao university from February 2020 to February 2021 were selected,depending on the type of diseases,patients can be divided into stroke group and combined group,45 cases each,stroke group for pure stroke patients,combined group for depression after stroke in patients with cognitive dysfunction patients,all patients of two groups were examined by the magnetic resonance perfusion weighted imaging(PWI),The relative cerebral blood flow(rCBF)values in different parts of the two groups were compared.Results The cerebral blood flow of the bilateral frontal lobe,left temporal lobe,and right basal ganglia of the combined group was significantly lower than that of the stroke group(P<0.05).There was no significant difference in cerebral blood flow between the two groups in bilateral parietal lobe,bilateral occipital lobe,right temporal lobe,left basal ganglia and bilateral cerebellum(P>0.05).The mean difference(-36.02845)and standard error(11.36253)between the two groups were statistically significant(P<0.05).Conclusion The occurrence of post-stroke depression combined with cognitive dysfunction is related to the decrease of blood perfusion in the bilateral frontal lobe,left temporal lobe,and right basal ganglia.